EPA Modulates KLK Genes via miR-378: A Potential Therapy in Prostate Cancer

It is known that miRNA-378a-3p (miR-378) could be induced by eicosapentaenoic acid (EPA), an omega-3 fatty acid. Herein, we first demonstrated how miR-378 exerts anti-prostate cancer (PCa) actions by influencing multiple target genes, including KLK2, KLK4, KLK6, and KLK14, which are implicated in PC...

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Bibliographic Details
Main Authors: Kai-Jie Yu, De-Yi Ji, Ming-Li Hsieh, Cheng-Keng Chuang, See-Tong Pang, Wen-Hui Weng
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/14/11/2813