The genus Porana (Convolvulaceae) - A phytochemical and pharmacological review
There are about 20 species of Porana Burm. f. worldwide in tropical and subtropical Asia, Africa and neighboring islands, Oceania, and the Americas. In China, India, and other places, this genus enjoys a wealth of experience in folk applications. Nevertheless, the chemical composition of only five s...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-10-01
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| Series: | Frontiers in Pharmacology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fphar.2022.998965/full |
| _version_ | 1811182109198385152 |
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| author | Yu Peng Yu Peng Ye Li Yuanyuan Yang Yuanqing Gao Hui Ren Jing Hu Xiaomin Cui Wenjing Lu Hongxun Tao Zhiyong Chen |
| author_facet | Yu Peng Yu Peng Ye Li Yuanyuan Yang Yuanqing Gao Hui Ren Jing Hu Xiaomin Cui Wenjing Lu Hongxun Tao Zhiyong Chen |
| author_sort | Yu Peng |
| collection | DOAJ |
| description | There are about 20 species of Porana Burm. f. worldwide in tropical and subtropical Asia, Africa and neighboring islands, Oceania, and the Americas. In China, India, and other places, this genus enjoys a wealth of experience in folk applications. Nevertheless, the chemical composition of only five species has been reported, and 59 compounds have been isolated and identified, including steroids, coumarins, flavonoids, quinic acid derivatives, and amides. Pharmacological studies revealed that extracts from this genus and their bioactive components exhibit anti-inflammatory, analgesic, antioxidant, anti-gout, anti-cancer, and anti-diabetic effects. Although this genus is abundant, the development of its pharmacological applications remains limited. This review will systematically summarize the traditional and current uses, chemical compositions, and pharmacological activities of various Porana species. Network analysis was introduced to compare and confirm its output with current research progress to explore the potential targets and pathways of chemical components in this genus. We hope to increase understanding of this genus’s medicinal value and suggest directions for rational medicinal development. |
| first_indexed | 2024-04-11T09:26:32Z |
| format | Article |
| id | doaj.art-1bd4e1d0ad0045cf8cb58c297c81f8a0 |
| institution | Directory Open Access Journal |
| issn | 1663-9812 |
| language | English |
| last_indexed | 2024-04-11T09:26:32Z |
| publishDate | 2022-10-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Pharmacology |
| spelling | doaj.art-1bd4e1d0ad0045cf8cb58c297c81f8a02022-12-22T04:32:00ZengFrontiers Media S.A.Frontiers in Pharmacology1663-98122022-10-011310.3389/fphar.2022.998965998965The genus Porana (Convolvulaceae) - A phytochemical and pharmacological reviewYu Peng0Yu Peng1Ye Li2Yuanyuan Yang3Yuanqing Gao4Hui Ren5Jing Hu6Xiaomin Cui7Wenjing Lu8Hongxun Tao9Zhiyong Chen10Shaanxi Academy of Traditional Chinese Medicine, Xi’an, Shaanxi, ChinaJiangsu Provincial Key Laboratory of Cardiovascular and Cerebrovascular Medicine, School of Pharmacy, Nanjing Medical University, Nanjing, Jiangsu, ChinaShaanxi Academy of Traditional Chinese Medicine, Xi’an, Shaanxi, ChinaXi’an Institute for Food and Drug Control, Xi’an, Shaanxi, ChinaJiangsu Provincial Key Laboratory of Cardiovascular and Cerebrovascular Medicine, School of Pharmacy, Nanjing Medical University, Nanjing, Jiangsu, ChinaShaanxi Academy of Traditional Chinese Medicine, Xi’an, Shaanxi, ChinaShaanxi Academy of Traditional Chinese Medicine, Xi’an, Shaanxi, ChinaShaanxi Academy of Traditional Chinese Medicine, Xi’an, Shaanxi, ChinaShaanxi Academy of Traditional Chinese Medicine, Xi’an, Shaanxi, ChinaSchool of Food and Biological Engineering, Jiangsu University, Zhenjiang, Jiangsu, ChinaShaanxi Academy of Traditional Chinese Medicine, Xi’an, Shaanxi, ChinaThere are about 20 species of Porana Burm. f. worldwide in tropical and subtropical Asia, Africa and neighboring islands, Oceania, and the Americas. In China, India, and other places, this genus enjoys a wealth of experience in folk applications. Nevertheless, the chemical composition of only five species has been reported, and 59 compounds have been isolated and identified, including steroids, coumarins, flavonoids, quinic acid derivatives, and amides. Pharmacological studies revealed that extracts from this genus and their bioactive components exhibit anti-inflammatory, analgesic, antioxidant, anti-gout, anti-cancer, and anti-diabetic effects. Although this genus is abundant, the development of its pharmacological applications remains limited. This review will systematically summarize the traditional and current uses, chemical compositions, and pharmacological activities of various Porana species. Network analysis was introduced to compare and confirm its output with current research progress to explore the potential targets and pathways of chemical components in this genus. We hope to increase understanding of this genus’s medicinal value and suggest directions for rational medicinal development.https://www.frontiersin.org/articles/10.3389/fphar.2022.998965/fullPorana burm. f.traditional usephytochemistrynetwork analysispharmacological activity |
| spellingShingle | Yu Peng Yu Peng Ye Li Yuanyuan Yang Yuanqing Gao Hui Ren Jing Hu Xiaomin Cui Wenjing Lu Hongxun Tao Zhiyong Chen The genus Porana (Convolvulaceae) - A phytochemical and pharmacological review Frontiers in Pharmacology Porana burm. f. traditional use phytochemistry network analysis pharmacological activity |
| title | The genus Porana (Convolvulaceae) - A phytochemical and pharmacological review |
| title_full | The genus Porana (Convolvulaceae) - A phytochemical and pharmacological review |
| title_fullStr | The genus Porana (Convolvulaceae) - A phytochemical and pharmacological review |
| title_full_unstemmed | The genus Porana (Convolvulaceae) - A phytochemical and pharmacological review |
| title_short | The genus Porana (Convolvulaceae) - A phytochemical and pharmacological review |
| title_sort | genus porana convolvulaceae a phytochemical and pharmacological review |
| topic | Porana burm. f. traditional use phytochemistry network analysis pharmacological activity |
| url | https://www.frontiersin.org/articles/10.3389/fphar.2022.998965/full |
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