Between-centre differences and treatment effects in randomized controlled trials: A case study in traumatic brain injury

Between-centre differences and treatment effects in randomized controlled trials: A case study in traumatic brain injury

<p>Abstract</p> <p>Background</p> <p>In Traumatic Brain Injury (TBI), large between-centre differences in outcome exist and many clinicians believe that such differences influence estimation of the treatment effect in randomized controlled trial (RCTs). The aim of this...

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Bibliographic Details
Main Authors: Roberts Ian, Perel Pablo, Roozenbeek Bob, Lingsma Hester F, Maas Andrew IR, Steyerberg Ewout W
Format: Article
Language:English
Published: BMC 2011-08-01
Series:Trials
Online Access:http://www.trialsjournal.com/content/12/1/201

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