Staphylococcus aureus Putative Vaccines Based on the Virulence Factors: A Mini-Review
Since the 1960s, the frequency of methicillin-resistant Staphylococcus aureus as a recurrent cause of nosocomial infections has increased. Since multidrug-resistant Staphylococcus has overcome antimicrobial treatment, the development of putative vaccines based on virulence factors could be a great h...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2021-09-01
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| Series: | Frontiers in Microbiology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fmicb.2021.704247/full |
| _version_ | 1818609861279088640 |
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| author | Bahman Mirzaei Ryhaneh Babaei Habib Zeighami Maryam Dadar Ali Soltani |
| author_facet | Bahman Mirzaei Ryhaneh Babaei Habib Zeighami Maryam Dadar Ali Soltani |
| author_sort | Bahman Mirzaei |
| collection | DOAJ |
| description | Since the 1960s, the frequency of methicillin-resistant Staphylococcus aureus as a recurrent cause of nosocomial infections has increased. Since multidrug-resistant Staphylococcus has overcome antimicrobial treatment, the development of putative vaccines based on virulence factors could be a great help in controlling the infections caused by bacteria and are actively being pursued in healthcare settings. This mini-review provides an overview of the recent progress in vaccine development, immunogenicity, and therapeutic features of some S. aureus macromolecules as putative vaccine candidates and their implications against human S. aureus-related infections. Based on the reviewed experiments, multivalent vaccines could prevent the promotion of the diseases caused by this bacterium and enhance the prevention chance of S. aureus infections. |
| first_indexed | 2024-12-16T15:05:16Z |
| format | Article |
| id | doaj.art-1bdb27b6553441e581d12fdab3904a67 |
| institution | Directory Open Access Journal |
| issn | 1664-302X |
| language | English |
| last_indexed | 2024-12-16T15:05:16Z |
| publishDate | 2021-09-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Microbiology |
| spelling | doaj.art-1bdb27b6553441e581d12fdab3904a672022-12-21T22:27:09ZengFrontiers Media S.A.Frontiers in Microbiology1664-302X2021-09-011210.3389/fmicb.2021.704247704247Staphylococcus aureus Putative Vaccines Based on the Virulence Factors: A Mini-ReviewBahman Mirzaei0Ryhaneh Babaei1Habib Zeighami2Maryam Dadar3Ali Soltani4Department of Medical Microbiology and Virology, School of Medicine, Zanjan University of Medical Sciences, Zanjan, IranDepartment of Medical Microbiology and Virology, School of Medicine, Zanjan University of Medical Sciences, Zanjan, IranDepartment of Medical Microbiology and Virology, School of Medicine, Zanjan University of Medical Sciences, Zanjan, IranRazi Vaccine and Serum Research Institute, Agricultural Research, Education and Extension Organization, Karaj, IranDepartment of English Language, Zanjan University of Medical Sciences, Zanjan, IranSince the 1960s, the frequency of methicillin-resistant Staphylococcus aureus as a recurrent cause of nosocomial infections has increased. Since multidrug-resistant Staphylococcus has overcome antimicrobial treatment, the development of putative vaccines based on virulence factors could be a great help in controlling the infections caused by bacteria and are actively being pursued in healthcare settings. This mini-review provides an overview of the recent progress in vaccine development, immunogenicity, and therapeutic features of some S. aureus macromolecules as putative vaccine candidates and their implications against human S. aureus-related infections. Based on the reviewed experiments, multivalent vaccines could prevent the promotion of the diseases caused by this bacterium and enhance the prevention chance of S. aureus infections.https://www.frontiersin.org/articles/10.3389/fmicb.2021.704247/fullcandidate vaccinesimmunoprophylaxisprophylaxisStaphylococcus aureusstaphylococcal infections Staphylococcus aureus |
| spellingShingle | Bahman Mirzaei Ryhaneh Babaei Habib Zeighami Maryam Dadar Ali Soltani Staphylococcus aureus Putative Vaccines Based on the Virulence Factors: A Mini-Review Frontiers in Microbiology candidate vaccines immunoprophylaxis prophylaxis Staphylococcus aureus staphylococcal infections Staphylococcus aureus |
| title | Staphylococcus aureus Putative Vaccines Based on the Virulence Factors: A Mini-Review |
| title_full | Staphylococcus aureus Putative Vaccines Based on the Virulence Factors: A Mini-Review |
| title_fullStr | Staphylococcus aureus Putative Vaccines Based on the Virulence Factors: A Mini-Review |
| title_full_unstemmed | Staphylococcus aureus Putative Vaccines Based on the Virulence Factors: A Mini-Review |
| title_short | Staphylococcus aureus Putative Vaccines Based on the Virulence Factors: A Mini-Review |
| title_sort | staphylococcus aureus putative vaccines based on the virulence factors a mini review |
| topic | candidate vaccines immunoprophylaxis prophylaxis Staphylococcus aureus staphylococcal infections Staphylococcus aureus |
| url | https://www.frontiersin.org/articles/10.3389/fmicb.2021.704247/full |
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