Tailoring Fibre Structure Enabled by X-ray Analytics for Targeted Biomedical Applications
The rising interest in designing fibres via spinning techniques combining the properties of various polymeric materials into advanced functionalised materials is directed towards targeted biomedical applications such as drug delivery, wearable sensors or tissue engineering. Understanding how these...
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| Format: | Article |
| Language: | deu |
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Swiss Chemical Society
2022-03-01
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| Series: | CHIMIA |
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| Online Access: | https://chimia.ch/chimia/article/view/5878 |
| _version_ | 1818286935883382784 |
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| author | Jean Schoeller Jonathan T. Avaro Anjani K. Maurya René M. Rossi Antonia Neels |
| author_facet | Jean Schoeller Jonathan T. Avaro Anjani K. Maurya René M. Rossi Antonia Neels |
| author_sort | Jean Schoeller |
| collection | DOAJ |
| description |
The rising interest in designing fibres via spinning techniques combining the properties of various polymeric materials into advanced functionalised materials is directed towards targeted biomedical applications such as drug delivery, wearable sensors or tissue engineering. Understanding how these functional polymers exhibit multiscale structures ranging from the molecular level to nano-, micro-and millimetre scale is a key prerequisite for their challenging applications that can be addressed by a non-destructive X-ray based analytical approach. X-ray multimodalities combining X-ray imaging, scattering and diffraction allow the study of morphology, molecular structure, and the analysis of nano-domain size and shape, crystallinity and preferential orientation in 3D arrangements. The incorporation of X-ray analytics in the design process of polymeric fibers via their nanostructure under non-ambient conditions (i.e. temperature, mechanical load, humidity…) allows for efficient optimization of the fabrication process as well as quality control along the product lifetime under operating environmental conditions. Here, we demonstrate the successful collaboration between the laboratory of Biomimetic Textiles and Membranes and the Center of X-ray Analytics at Empa for the design, characterisation and optimisation of advanced functionalised polymeric fibrous material systems.
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| first_indexed | 2024-12-13T01:32:30Z |
| format | Article |
| id | doaj.art-1bddea700b41413f9ed25c14febf9beb |
| institution | Directory Open Access Journal |
| issn | 0009-4293 2673-2424 |
| language | deu |
| last_indexed | 2024-12-13T01:32:30Z |
| publishDate | 2022-03-01 |
| publisher | Swiss Chemical Society |
| record_format | Article |
| series | CHIMIA |
| spelling | doaj.art-1bddea700b41413f9ed25c14febf9beb2022-12-22T00:03:57ZdeuSwiss Chemical SocietyCHIMIA0009-42932673-24242022-03-0176310.2533/chimia.2022.229Tailoring Fibre Structure Enabled by X-ray Analytics for Targeted Biomedical ApplicationsJean Schoeller0Jonathan T. Avaro1Anjani K. Maurya2René M. Rossi3Antonia Neels 4Empa, Swiss Federal Laboratories for Materials Science and Technology, Laboratory for Biomimetic Membranes and Textiles, 9014 St. Gallen, Switzerland. ; 2 ETH Zürich, Department of Health Science and Technology, 8093 Zürich, SwitzerlandEmpa, Swiss Federal Laboratories for Materials Science and Technology, Center for X-ray Analytics, 8600 Dübendorf, Switzerland;Empa, Swiss Federal Laboratories for Materials Science and Technology, Center for X-ray Analytics, 8600 Dübendorf, Switzerland; Current address: Stanford Synchrotron Radiation Lightsource, SLAC National Accelerator Laboratory, Menlo Park, CA, 94025 USA. 1 Empa, Swiss Federal Laboratories for Materials Science and Technology, Laboratory for Biomimetic Membranes and Textiles, 9014 St. Gallen, Switzerland; 2 ETH Zürich, Department of Health Science and Technology, 8093 Zürich, Switzerland;3 Empa, Swiss Federal Laboratories for Materials Science and Technology, Center for X-ray Analytics, 8600 Dübendorf, Switzerland; 4 University of Fribourg, Department of Chemistry, Chemin du Musée 9, 1700 Fribourg, Switzerland, Switzerland The rising interest in designing fibres via spinning techniques combining the properties of various polymeric materials into advanced functionalised materials is directed towards targeted biomedical applications such as drug delivery, wearable sensors or tissue engineering. Understanding how these functional polymers exhibit multiscale structures ranging from the molecular level to nano-, micro-and millimetre scale is a key prerequisite for their challenging applications that can be addressed by a non-destructive X-ray based analytical approach. X-ray multimodalities combining X-ray imaging, scattering and diffraction allow the study of morphology, molecular structure, and the analysis of nano-domain size and shape, crystallinity and preferential orientation in 3D arrangements. The incorporation of X-ray analytics in the design process of polymeric fibers via their nanostructure under non-ambient conditions (i.e. temperature, mechanical load, humidity…) allows for efficient optimization of the fabrication process as well as quality control along the product lifetime under operating environmental conditions. Here, we demonstrate the successful collaboration between the laboratory of Biomimetic Textiles and Membranes and the Center of X-ray Analytics at Empa for the design, characterisation and optimisation of advanced functionalised polymeric fibrous material systems. https://chimia.ch/chimia/article/view/5878FibresX-ray multi-modalitiesNano-StructureFunctionality |
| spellingShingle | Jean Schoeller Jonathan T. Avaro Anjani K. Maurya René M. Rossi Antonia Neels Tailoring Fibre Structure Enabled by X-ray Analytics for Targeted Biomedical Applications CHIMIA Fibres X-ray multi-modalities Nano-Structure Functionality |
| title | Tailoring Fibre Structure Enabled by X-ray Analytics for Targeted Biomedical Applications |
| title_full | Tailoring Fibre Structure Enabled by X-ray Analytics for Targeted Biomedical Applications |
| title_fullStr | Tailoring Fibre Structure Enabled by X-ray Analytics for Targeted Biomedical Applications |
| title_full_unstemmed | Tailoring Fibre Structure Enabled by X-ray Analytics for Targeted Biomedical Applications |
| title_short | Tailoring Fibre Structure Enabled by X-ray Analytics for Targeted Biomedical Applications |
| title_sort | tailoring fibre structure enabled by x ray analytics for targeted biomedical applications |
| topic | Fibres X-ray multi-modalities Nano-Structure Functionality |
| url | https://chimia.ch/chimia/article/view/5878 |
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