A proteomic study to unveil lead toxicity-induced memory impairments invoked by synaptic dysregulation

A proteomic study to unveil lead toxicity-induced memory impairments invoked by synaptic dysregulation

Lead (Pb2+), a ubiquitously present heavy metal toxin, has various detrimental effects on memory and cognition. However, the molecular processes affected by Pb2+ causing structural and functional anomalies are still unclear. To explore this, we employed behavioral and proteomic approaches using rat...

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Bibliographic Details
Main Authors: Nivedha Mohanraj, Neha S. Joshi, Roshni Poulose, Rahul R. Patil, Rashmi Santhoshkumar, Anubhav Kumar, Girish P. Waghmare, Amit Kumar Saha, Syeda Zehra Haider, Yogananda S. Markandeya, Gourav Dey, Laxmi T. Rao, Periyasamy Govindaraj, Bhupesh Mehta
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:Toxicology Reports
Subjects:
Lead toxicity
Synaptosome
Memory
Cognitive impairment
Proteomics
SUMO
Online Access:http://www.sciencedirect.com/science/article/pii/S2214750022001561

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