Renal protective effect and mechanism research of hypoxia inducible factor-1α inhibitor YC-1 in diabetic nephropathy mice
Objective·To investigate the effect of hypoxia inducible factor-1α (HIF-1α) inhibitor YC-1 on the progression of diabetic nephropathy (DN) in mice and the potential mechanism.Methods·Ten-week-old male db/db mice (DN model) and their nondiabetic wild-type (WT) littermates were divided into 4 groups (...
Main Authors: | , , , , , |
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Format: | Article |
Language: | zho |
Published: |
Editorial Office of Journal of Shanghai Jiao Tong University (Medical Science)
2023-09-01
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Series: | Shanghai Jiaotong Daxue xuebao. Yixue ban |
Subjects: | |
Online Access: | https://xuebao.shsmu.edu.cn/article/2023/1674-8115/1674-8115-2023-43-9-1089.shtml |