A randomized clinical trial demonstrating cell type specific effects of hyperlipidemia and hyperinsulinemia on pituitary function.

<h4>Introduction</h4>Obesity is characterized by elevated lipids, insulin resistance and relative hypogonadotropic hypogonadism, reducing fertility and increasing risk of pregnancy complications and birth defects. We termed this phenotype 'Reprometabolic Syndrome' and showed th...

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Bibliographic Details
Main Authors: Rosemary McDonald, Katherine Kuhn, Thy B Nguyen, Andrew Tannous, Irene Schauer, Nanette Santoro, Andrew P Bradford
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0268323