Beneficial Effects of Laurel (<i>Laurus nobilis</i> L.) and Myrtle (<i>Myrtus communis</i> L.) Extract on Rat Health
Polyphenols of Laurel and Myrtle exhibit structural diversity, which affects bioavailability, metabolism, and bioactivity. The gut microbiota plays a key role in modulating the production, bioavailability and, thus the biological activities of phenolic metabolites, particularly after the intake of f...
| Main Authors: | , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2022-01-01
|
| Series: | Molecules |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1420-3049/27/2/581 |
| _version_ | 1797491453001203712 |
|---|---|
| author | Marija Berendika Sandra Domjanić Drozdek Dyana Odeh Nada Oršolić Petar Dragičević Marijana Sokolović Ivona Elez Garofulić Domagoj Đikić Irena Landeka Jurčević |
| author_facet | Marija Berendika Sandra Domjanić Drozdek Dyana Odeh Nada Oršolić Petar Dragičević Marijana Sokolović Ivona Elez Garofulić Domagoj Đikić Irena Landeka Jurčević |
| author_sort | Marija Berendika |
| collection | DOAJ |
| description | Polyphenols of Laurel and Myrtle exhibit structural diversity, which affects bioavailability, metabolism, and bioactivity. The gut microbiota plays a key role in modulating the production, bioavailability and, thus the biological activities of phenolic metabolites, particularly after the intake of food containing high-molecular-weight polyphenols. The aim of this study was to investigate whether the polyphenolic components of Laurel and Myrtle aqueous extract have beneficial effects on rat health. The growth of lactic acid bacteria (LAB), β-glucuronidase, β-glucosidase, β-galactosidase activity, pH value, body weight change and food efficacy ratio after intragastric treatment of rats with Laurel and Myrtle extract at doses of 50 and 100 mg/kg for two weeks were investigated. The endogenous populations of colonic probiotic bacteria (Lactobacilli and Bifidobacteria) were counted on selective media. According to the obtained data, Laurel extract in the applied dose of 50 and 100 and Myrtle extract (100 mg/kg) positively affects the rats health by increasing the number of colonies of Lactobacilli and Bifidobacteria compared to the control group, causes changes in glycolytic enzymatic activity and minor change in antioxidative tissue activity. In addition, high doses of Laurel increase food efficiency ratio, while Myrtle has the same effect at a lower dose. |
| first_indexed | 2024-03-10T00:48:40Z |
| format | Article |
| id | doaj.art-1becd661e51b47f681f18bb3fce9a63b |
| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-03-10T00:48:40Z |
| publishDate | 2022-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj.art-1becd661e51b47f681f18bb3fce9a63b2023-11-23T14:54:04ZengMDPI AGMolecules1420-30492022-01-0127258110.3390/molecules27020581Beneficial Effects of Laurel (<i>Laurus nobilis</i> L.) and Myrtle (<i>Myrtus communis</i> L.) Extract on Rat HealthMarija Berendika0Sandra Domjanić Drozdek1Dyana Odeh2Nada Oršolić3Petar Dragičević4Marijana Sokolović5Ivona Elez Garofulić6Domagoj Đikić7Irena Landeka Jurčević8Department of Food Quality Control, Faculty of Food Technology and Biotechnology, University of Zagreb, Pierottijeva 6, 10000 Zagreb, CroatiaDepartment of Food Quality Control, Faculty of Food Technology and Biotechnology, University of Zagreb, Pierottijeva 6, 10000 Zagreb, CroatiaDepartment of Animal Physiology, Faculty of Science, University of Zagreb, Rooseveltov trg 6, 10000 Zagreb, CroatiaDepartment of Animal Physiology, Faculty of Science, University of Zagreb, Rooseveltov trg 6, 10000 Zagreb, CroatiaSchool of Medicine, University of Zagreb, Šalata 3, 10000 Zagreb, CroatiaCroatian Veterinary Institute Zagreb, Savska Cesta 143, 10000 Zagreb, CroatiaDepartment of Food Quality Control, Faculty of Food Technology and Biotechnology, University of Zagreb, Pierottijeva 6, 10000 Zagreb, CroatiaDepartment of Animal Physiology, Faculty of Science, University of Zagreb, Rooseveltov trg 6, 10000 Zagreb, CroatiaDepartment of Food Quality Control, Faculty of Food Technology and Biotechnology, University of Zagreb, Pierottijeva 6, 10000 Zagreb, CroatiaPolyphenols of Laurel and Myrtle exhibit structural diversity, which affects bioavailability, metabolism, and bioactivity. The gut microbiota plays a key role in modulating the production, bioavailability and, thus the biological activities of phenolic metabolites, particularly after the intake of food containing high-molecular-weight polyphenols. The aim of this study was to investigate whether the polyphenolic components of Laurel and Myrtle aqueous extract have beneficial effects on rat health. The growth of lactic acid bacteria (LAB), β-glucuronidase, β-glucosidase, β-galactosidase activity, pH value, body weight change and food efficacy ratio after intragastric treatment of rats with Laurel and Myrtle extract at doses of 50 and 100 mg/kg for two weeks were investigated. The endogenous populations of colonic probiotic bacteria (Lactobacilli and Bifidobacteria) were counted on selective media. According to the obtained data, Laurel extract in the applied dose of 50 and 100 and Myrtle extract (100 mg/kg) positively affects the rats health by increasing the number of colonies of Lactobacilli and Bifidobacteria compared to the control group, causes changes in glycolytic enzymatic activity and minor change in antioxidative tissue activity. In addition, high doses of Laurel increase food efficiency ratio, while Myrtle has the same effect at a lower dose.https://www.mdpi.com/1420-3049/27/2/581Laurel extractMyrtle extractgut microbial enzyme activityantioxidative activity in tissueprobiotic bacteria |
| spellingShingle | Marija Berendika Sandra Domjanić Drozdek Dyana Odeh Nada Oršolić Petar Dragičević Marijana Sokolović Ivona Elez Garofulić Domagoj Đikić Irena Landeka Jurčević Beneficial Effects of Laurel (<i>Laurus nobilis</i> L.) and Myrtle (<i>Myrtus communis</i> L.) Extract on Rat Health Molecules Laurel extract Myrtle extract gut microbial enzyme activity antioxidative activity in tissue probiotic bacteria |
| title | Beneficial Effects of Laurel (<i>Laurus nobilis</i> L.) and Myrtle (<i>Myrtus communis</i> L.) Extract on Rat Health |
| title_full | Beneficial Effects of Laurel (<i>Laurus nobilis</i> L.) and Myrtle (<i>Myrtus communis</i> L.) Extract on Rat Health |
| title_fullStr | Beneficial Effects of Laurel (<i>Laurus nobilis</i> L.) and Myrtle (<i>Myrtus communis</i> L.) Extract on Rat Health |
| title_full_unstemmed | Beneficial Effects of Laurel (<i>Laurus nobilis</i> L.) and Myrtle (<i>Myrtus communis</i> L.) Extract on Rat Health |
| title_short | Beneficial Effects of Laurel (<i>Laurus nobilis</i> L.) and Myrtle (<i>Myrtus communis</i> L.) Extract on Rat Health |
| title_sort | beneficial effects of laurel i laurus nobilis i l and myrtle i myrtus communis i l extract on rat health |
| topic | Laurel extract Myrtle extract gut microbial enzyme activity antioxidative activity in tissue probiotic bacteria |
| url | https://www.mdpi.com/1420-3049/27/2/581 |
| work_keys_str_mv | AT marijaberendika beneficialeffectsoflaurelilaurusnobilisilandmyrtleimyrtuscommunisilextractonrathealth AT sandradomjanicdrozdek beneficialeffectsoflaurelilaurusnobilisilandmyrtleimyrtuscommunisilextractonrathealth AT dyanaodeh beneficialeffectsoflaurelilaurusnobilisilandmyrtleimyrtuscommunisilextractonrathealth AT nadaorsolic beneficialeffectsoflaurelilaurusnobilisilandmyrtleimyrtuscommunisilextractonrathealth AT petardragicevic beneficialeffectsoflaurelilaurusnobilisilandmyrtleimyrtuscommunisilextractonrathealth AT marijanasokolovic beneficialeffectsoflaurelilaurusnobilisilandmyrtleimyrtuscommunisilextractonrathealth AT ivonaelezgarofulic beneficialeffectsoflaurelilaurusnobilisilandmyrtleimyrtuscommunisilextractonrathealth AT domagojđikic beneficialeffectsoflaurelilaurusnobilisilandmyrtleimyrtuscommunisilextractonrathealth AT irenalandekajurcevic beneficialeffectsoflaurelilaurusnobilisilandmyrtleimyrtuscommunisilextractonrathealth |