A case series of CMV infections in infants and its inoppurtune immuno-hematological manifestations

Congenital cytomegalovirus (CMV) infection is rampant viral disease, one of the commonest non-genetic cause for neurodevelopmental delay which is often under diagnosed. Leukemoid reaction, Hemophagocytic Lymphohistiocytosis (HLH) and autoimmune cytopenias are rare hematological manifestations of CMV...

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Main Authors: Abhilasha Sampagar, Pratima D. Patil, Taiseenub Patel, Shiv Dubey
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:Pediatric Hematology Oncology Journal
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S246812452200242X
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author Abhilasha Sampagar
Pratima D. Patil
Taiseenub Patel
Shiv Dubey
author_facet Abhilasha Sampagar
Pratima D. Patil
Taiseenub Patel
Shiv Dubey
author_sort Abhilasha Sampagar
collection DOAJ
description Congenital cytomegalovirus (CMV) infection is rampant viral disease, one of the commonest non-genetic cause for neurodevelopmental delay which is often under diagnosed. Leukemoid reaction, Hemophagocytic Lymphohistiocytosis (HLH) and autoimmune cytopenias are rare hematological manifestations of CMV infection. There is paucity of literature regarding hematological manifestation in CMV infection. Here we present four cases of CMV infection with different hematological findings where early diagnosis and prompt intervention resulted in good outcome.
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spelling doaj.art-1bef77086ce6498d89bccefae6e2203b2022-12-29T04:13:42ZengElsevierPediatric Hematology Oncology Journal2468-12452022-12-0174119121A case series of CMV infections in infants and its inoppurtune immuno-hematological manifestationsAbhilasha Sampagar0Pratima D. Patil1Taiseenub Patel2Shiv Dubey3Department of Paediatrics, Jawaharlal Nehru Medical College, KLE Academy of Higher Education and Research, Belagavi, India; Corresponding author.Department of Paediatrics, Jawaharlal Nehru Medical College, KLE Academy of Higher Education and Research, Belagavi, IndiaDepartment of Paediatrics, Jawaharlal Nehru Medical College, KLE Academy of Higher Education and Research, Belagavi, IndiaDepartment of Paediatrics, Jawaharlal Nehru Medical College, KLE Academy of Higher Education and Research, Belagavi, IndiaCongenital cytomegalovirus (CMV) infection is rampant viral disease, one of the commonest non-genetic cause for neurodevelopmental delay which is often under diagnosed. Leukemoid reaction, Hemophagocytic Lymphohistiocytosis (HLH) and autoimmune cytopenias are rare hematological manifestations of CMV infection. There is paucity of literature regarding hematological manifestation in CMV infection. Here we present four cases of CMV infection with different hematological findings where early diagnosis and prompt intervention resulted in good outcome.http://www.sciencedirect.com/science/article/pii/S246812452200242XCytomegalovirus infectionHaemophagocytic lymphohistiocytosisAutoimmune hemolytic anemia
spellingShingle Abhilasha Sampagar
Pratima D. Patil
Taiseenub Patel
Shiv Dubey
A case series of CMV infections in infants and its inoppurtune immuno-hematological manifestations
Pediatric Hematology Oncology Journal
Cytomegalovirus infection
Haemophagocytic lymphohistiocytosis
Autoimmune hemolytic anemia
title A case series of CMV infections in infants and its inoppurtune immuno-hematological manifestations
title_full A case series of CMV infections in infants and its inoppurtune immuno-hematological manifestations
title_fullStr A case series of CMV infections in infants and its inoppurtune immuno-hematological manifestations
title_full_unstemmed A case series of CMV infections in infants and its inoppurtune immuno-hematological manifestations
title_short A case series of CMV infections in infants and its inoppurtune immuno-hematological manifestations
title_sort case series of cmv infections in infants and its inoppurtune immuno hematological manifestations
topic Cytomegalovirus infection
Haemophagocytic lymphohistiocytosis
Autoimmune hemolytic anemia
url http://www.sciencedirect.com/science/article/pii/S246812452200242X
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