Rational design of pyrrole derivatives with aggregation-induced phosphorescence characteristics for time-resolved and two-photon luminescence imaging
Aggregation-induced emission (AIE) fluorescence probes are indispensable for biomedical imaging, however, interference with tissue autofluorescence results in low signal-to-noise ratio limiting the development of bioimaging with AIE materials. Here the authors develop AIEgen room-temperature phospho...
| Main Authors: | , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2021-08-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-021-25174-6 |
| _version_ | 1818998296881922048 |
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| author | Jianhui Yang Yahui Zhang Xinghui Wu Wenbo Dai Dan Chen Jianbing Shi Bin Tong Qian Peng Haiyan Xie Zhengxu Cai Yuping Dong Xin Zhang |
| author_facet | Jianhui Yang Yahui Zhang Xinghui Wu Wenbo Dai Dan Chen Jianbing Shi Bin Tong Qian Peng Haiyan Xie Zhengxu Cai Yuping Dong Xin Zhang |
| author_sort | Jianhui Yang |
| collection | DOAJ |
| description | Aggregation-induced emission (AIE) fluorescence probes are indispensable for biomedical imaging, however, interference with tissue autofluorescence results in low signal-to-noise ratio limiting the development of bioimaging with AIE materials. Here the authors develop AIEgen room-temperature phosphors with long emission lifetimes efficiently eliminating intereference with the background signal in imaging. |
| first_indexed | 2024-12-20T21:59:17Z |
| format | Article |
| id | doaj.art-1bf039bbdda54b79b9e4fe2247a944fe |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-12-20T21:59:17Z |
| publishDate | 2021-08-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-1bf039bbdda54b79b9e4fe2247a944fe2022-12-21T19:25:23ZengNature PortfolioNature Communications2041-17232021-08-011211810.1038/s41467-021-25174-6Rational design of pyrrole derivatives with aggregation-induced phosphorescence characteristics for time-resolved and two-photon luminescence imagingJianhui Yang0Yahui Zhang1Xinghui Wu2Wenbo Dai3Dan Chen4Jianbing Shi5Bin Tong6Qian Peng7Haiyan Xie8Zhengxu Cai9Yuping Dong10Xin Zhang11Beijing Key Laboratory of Construction Tailorable Advanced Functional Materials and Green Applications, School of Materials Science and Engineering, Beijing Institute of TechnologySchool of Life Science, Advanced Research Institute of Multidisciplinary Science, Beijing Institute of TechnologyBeijing Key Laboratory of Construction Tailorable Advanced Functional Materials and Green Applications, School of Materials Science and Engineering, Beijing Institute of TechnologyBeijing Key Laboratory of Construction Tailorable Advanced Functional Materials and Green Applications, School of Materials Science and Engineering, Beijing Institute of TechnologyDepartment of Gynaecology, Cancer Hospital of China Medical University, Liaoning Cancer HospitalBeijing Key Laboratory of Construction Tailorable Advanced Functional Materials and Green Applications, School of Materials Science and Engineering, Beijing Institute of TechnologyBeijing Key Laboratory of Construction Tailorable Advanced Functional Materials and Green Applications, School of Materials Science and Engineering, Beijing Institute of TechnologySchool of Chemical Sciences, University of Chinese Academy of SciencesSchool of Life Science, Advanced Research Institute of Multidisciplinary Science, Beijing Institute of TechnologyBeijing Key Laboratory of Construction Tailorable Advanced Functional Materials and Green Applications, School of Materials Science and Engineering, Beijing Institute of TechnologyBeijing Key Laboratory of Construction Tailorable Advanced Functional Materials and Green Applications, School of Materials Science and Engineering, Beijing Institute of TechnologyDepartment of Gynaecology, Cancer Hospital of China Medical University, Liaoning Cancer HospitalAggregation-induced emission (AIE) fluorescence probes are indispensable for biomedical imaging, however, interference with tissue autofluorescence results in low signal-to-noise ratio limiting the development of bioimaging with AIE materials. Here the authors develop AIEgen room-temperature phosphors with long emission lifetimes efficiently eliminating intereference with the background signal in imaging.https://doi.org/10.1038/s41467-021-25174-6 |
| spellingShingle | Jianhui Yang Yahui Zhang Xinghui Wu Wenbo Dai Dan Chen Jianbing Shi Bin Tong Qian Peng Haiyan Xie Zhengxu Cai Yuping Dong Xin Zhang Rational design of pyrrole derivatives with aggregation-induced phosphorescence characteristics for time-resolved and two-photon luminescence imaging Nature Communications |
| title | Rational design of pyrrole derivatives with aggregation-induced phosphorescence characteristics for time-resolved and two-photon luminescence imaging |
| title_full | Rational design of pyrrole derivatives with aggregation-induced phosphorescence characteristics for time-resolved and two-photon luminescence imaging |
| title_fullStr | Rational design of pyrrole derivatives with aggregation-induced phosphorescence characteristics for time-resolved and two-photon luminescence imaging |
| title_full_unstemmed | Rational design of pyrrole derivatives with aggregation-induced phosphorescence characteristics for time-resolved and two-photon luminescence imaging |
| title_short | Rational design of pyrrole derivatives with aggregation-induced phosphorescence characteristics for time-resolved and two-photon luminescence imaging |
| title_sort | rational design of pyrrole derivatives with aggregation induced phosphorescence characteristics for time resolved and two photon luminescence imaging |
| url | https://doi.org/10.1038/s41467-021-25174-6 |
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