Generation of FOS gene knockout lines from a human embryonic stem cell line using CRISPR/Cas9

Generation of FOS gene knockout lines from a human embryonic stem cell line using CRISPR/Cas9

Abstact: FOS is component of the AP-1 complex and has been reported to be involved in many cellular functions, including cell proliferation, differentiation, survival, angiogenesis, hematopoiesis and cancer progress. To further understand the exact role of FOS in these processes, here we created two...

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Bibliographic Details
Main Authors: Chunfu Li, Qing Wang, Zhiyong Peng, Yuchen Lin, Huaying Liu, Xiuling Yang, Shan Li, XiaoTing Liu, Jingru Chen
Format: Article
Language:English
Published: Elsevier 2019-08-01
Series:Stem Cell Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506119301096

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