West Nile Virus Lineage 2 Vector Competence of Indigenous <i>Culex</i> and <i>Aedes</i> Mosquitoes from Germany at Temperate Climate Conditions
West Nile virus (WNV) is a widespread zoonotic arbovirus and a threat to public health in Germany since its first emergence in 2018. It has become of particular relevance in Germany in 2019 due to its rapid geographical spread and the detection of the first human clinical cases. The susceptibility o...
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MDPI AG
2020-05-01
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| Series: | Viruses |
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| Online Access: | https://www.mdpi.com/1999-4915/12/5/561 |
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| author | Cora M. Holicki Ute Ziegler Cristian Răileanu Helge Kampen Doreen Werner Jana Schulz Cornelia Silaghi Martin H. Groschup Ana Vasić |
| author_facet | Cora M. Holicki Ute Ziegler Cristian Răileanu Helge Kampen Doreen Werner Jana Schulz Cornelia Silaghi Martin H. Groschup Ana Vasić |
| author_sort | Cora M. Holicki |
| collection | DOAJ |
| description | West Nile virus (WNV) is a widespread zoonotic arbovirus and a threat to public health in Germany since its first emergence in 2018. It has become of particular relevance in Germany in 2019 due to its rapid geographical spread and the detection of the first human clinical cases. The susceptibility of indigenous <i>Culex pipiens</i> (biotypes <i>pipiens</i> and <i>molestus</i>) for a German WNV lineage 2 strain was experimentally compared to that of Serbian <i>Cx. pipiens</i> biotype <i>molestus</i> and invasive German <i>Aedes albopictus</i>. All tested populations proved to be competent laboratory vectors of WNV. <i>Culex pipiens</i> biotype <i>pipiens</i> displayed the highest transmission efficiencies (40.0%–52.9%) at 25 °C. This biotype was also able to transmit WNV at 18 °C (transmission efficiencies of 4.4%–8.3%), proving that temperate climates in Central and Northern Europe may support WNV circulation. Furthermore, due to their feeding behaviors, <i>Cx. pipiens</i> biotype <i>molestus</i> and <i>Ae. albopictus</i> can act as “bridge vectors”, leading to human WNV infections. |
| first_indexed | 2024-03-10T19:44:26Z |
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| institution | Directory Open Access Journal |
| issn | 1999-4915 |
| language | English |
| last_indexed | 2024-03-10T19:44:26Z |
| publishDate | 2020-05-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Viruses |
| spelling | doaj.art-1bf1c7fa4f7a418e8786780a539440b92023-11-20T00:56:32ZengMDPI AGViruses1999-49152020-05-0112556110.3390/v12050561West Nile Virus Lineage 2 Vector Competence of Indigenous <i>Culex</i> and <i>Aedes</i> Mosquitoes from Germany at Temperate Climate ConditionsCora M. Holicki0Ute Ziegler1Cristian Răileanu2Helge Kampen3Doreen Werner4Jana Schulz5Cornelia Silaghi6Martin H. Groschup7Ana Vasić8Institute of Novel and Emerging Infectious Diseases, Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, 17493 Greifswald-Insel Riems, GermanyInstitute of Novel and Emerging Infectious Diseases, Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, 17493 Greifswald-Insel Riems, GermanyInstitute of Infectology, Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, 17493 Greifswald-Insel Riems, GermanyInstitute of Infectology, Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, 17493 Greifswald-Insel Riems, GermanyBiodiversity of Aquatic and Semiaquatic Landscape Features, Leibniz-Centre for Agricultural Landscape Research, 15374 Muencheberg, GermanyInstitute of Novel and Emerging Infectious Diseases, Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, 17493 Greifswald-Insel Riems, GermanyInstitute of Infectology, Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, 17493 Greifswald-Insel Riems, GermanyInstitute of Novel and Emerging Infectious Diseases, Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, 17493 Greifswald-Insel Riems, GermanyInstitute of Infectology, Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, 17493 Greifswald-Insel Riems, GermanyWest Nile virus (WNV) is a widespread zoonotic arbovirus and a threat to public health in Germany since its first emergence in 2018. It has become of particular relevance in Germany in 2019 due to its rapid geographical spread and the detection of the first human clinical cases. The susceptibility of indigenous <i>Culex pipiens</i> (biotypes <i>pipiens</i> and <i>molestus</i>) for a German WNV lineage 2 strain was experimentally compared to that of Serbian <i>Cx. pipiens</i> biotype <i>molestus</i> and invasive German <i>Aedes albopictus</i>. All tested populations proved to be competent laboratory vectors of WNV. <i>Culex pipiens</i> biotype <i>pipiens</i> displayed the highest transmission efficiencies (40.0%–52.9%) at 25 °C. This biotype was also able to transmit WNV at 18 °C (transmission efficiencies of 4.4%–8.3%), proving that temperate climates in Central and Northern Europe may support WNV circulation. Furthermore, due to their feeding behaviors, <i>Cx. pipiens</i> biotype <i>molestus</i> and <i>Ae. albopictus</i> can act as “bridge vectors”, leading to human WNV infections.https://www.mdpi.com/1999-4915/12/5/561West Nile virusvector competencetransmissionarbovirus<i>Culex pipiens</i><i>Aedes albopictus</i> |
| spellingShingle | Cora M. Holicki Ute Ziegler Cristian Răileanu Helge Kampen Doreen Werner Jana Schulz Cornelia Silaghi Martin H. Groschup Ana Vasić West Nile Virus Lineage 2 Vector Competence of Indigenous <i>Culex</i> and <i>Aedes</i> Mosquitoes from Germany at Temperate Climate Conditions Viruses West Nile virus vector competence transmission arbovirus <i>Culex pipiens</i> <i>Aedes albopictus</i> |
| title | West Nile Virus Lineage 2 Vector Competence of Indigenous <i>Culex</i> and <i>Aedes</i> Mosquitoes from Germany at Temperate Climate Conditions |
| title_full | West Nile Virus Lineage 2 Vector Competence of Indigenous <i>Culex</i> and <i>Aedes</i> Mosquitoes from Germany at Temperate Climate Conditions |
| title_fullStr | West Nile Virus Lineage 2 Vector Competence of Indigenous <i>Culex</i> and <i>Aedes</i> Mosquitoes from Germany at Temperate Climate Conditions |
| title_full_unstemmed | West Nile Virus Lineage 2 Vector Competence of Indigenous <i>Culex</i> and <i>Aedes</i> Mosquitoes from Germany at Temperate Climate Conditions |
| title_short | West Nile Virus Lineage 2 Vector Competence of Indigenous <i>Culex</i> and <i>Aedes</i> Mosquitoes from Germany at Temperate Climate Conditions |
| title_sort | west nile virus lineage 2 vector competence of indigenous i culex i and i aedes i mosquitoes from germany at temperate climate conditions |
| topic | West Nile virus vector competence transmission arbovirus <i>Culex pipiens</i> <i>Aedes albopictus</i> |
| url | https://www.mdpi.com/1999-4915/12/5/561 |
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