Prognostic value of body mass index before treatment for laryngeal squamous cell carcinoma
<b>Objective:</b>Patients with head and neck cancer often suffer from malnutrition. This study aims to investigate the influence of body mass index (BMI) on the prognosis of laryngeal squamous cell carcinoma (LSCC).<br/><b>Methods:</b>A total of 473 patients with LSCC i...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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China Anti-Cancer Association
2015-12-01
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| Series: | Cancer Biology & Medicine |
| Subjects: | |
| Online Access: | http://www.cancerbiomed.org/index.php/cocr/article/view/893 |
| _version_ | 1831775979404525568 |
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| author | Zhao-Qu Li Lan Zou Tian-Run Liu An-Kui Yang |
| author_facet | Zhao-Qu Li Lan Zou Tian-Run Liu An-Kui Yang |
| author_sort | Zhao-Qu Li |
| collection | DOAJ |
| description | <b>Objective:</b>Patients with head and neck cancer often suffer from malnutrition. This study aims to investigate the influence of body mass index (BMI) on the prognosis of laryngeal squamous cell carcinoma (LSCC).<br/><b>Methods:</b>A total of 473 patients with LSCC initially treated at Sun Yat-sen University Cancer Center between January 2005 and July 2009 were retrospectively reviewed. Survival analysis was performed by the Kaplan-Meier method and Cox regression model.<br/><b>Results:</b>Low BMI before treatment was significantly associated with poor overall survival in patients with LSCC (<i>P</i><0.001). BMI was an independent prognostic factor for patients with LSCC.<br/><b>Conclusion:</b>Leanness before treatment was associated with poor prognosis in patients with LSCC. Good nutritional status is favorable to improve survival in patients with LSCC. |
| first_indexed | 2024-12-22T09:25:12Z |
| format | Article |
| id | doaj.art-1bf271e0da264dc0be7861c2885a6afc |
| institution | Directory Open Access Journal |
| issn | 2095-3941 2095-3941 |
| language | English |
| last_indexed | 2024-12-22T09:25:12Z |
| publishDate | 2015-12-01 |
| publisher | China Anti-Cancer Association |
| record_format | Article |
| series | Cancer Biology & Medicine |
| spelling | doaj.art-1bf271e0da264dc0be7861c2885a6afc2022-12-21T18:31:06ZengChina Anti-Cancer AssociationCancer Biology & Medicine2095-39412095-39412015-12-0112439440010.7497/j.issn.2095-3941.2015.00432015000043Prognostic value of body mass index before treatment for laryngeal squamous cell carcinomaZhao-Qu Li0Lan Zou1Tian-Run Liu2An-Kui Yang3Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center of Cancer Medicine, Guangzhou 510060, China;Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center of Cancer Medicine, Guangzhou 510060, China;Department of Otorhinolaryngology Head and Neck Surgery, The Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou 510060, ChinaSun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center of Cancer Medicine, Guangzhou 510060, China;<b>Objective:</b>Patients with head and neck cancer often suffer from malnutrition. This study aims to investigate the influence of body mass index (BMI) on the prognosis of laryngeal squamous cell carcinoma (LSCC).<br/><b>Methods:</b>A total of 473 patients with LSCC initially treated at Sun Yat-sen University Cancer Center between January 2005 and July 2009 were retrospectively reviewed. Survival analysis was performed by the Kaplan-Meier method and Cox regression model.<br/><b>Results:</b>Low BMI before treatment was significantly associated with poor overall survival in patients with LSCC (<i>P</i><0.001). BMI was an independent prognostic factor for patients with LSCC.<br/><b>Conclusion:</b>Leanness before treatment was associated with poor prognosis in patients with LSCC. Good nutritional status is favorable to improve survival in patients with LSCC.http://www.cancerbiomed.org/index.php/cocr/article/view/893Prognosisnutritionbody mass index (BMI)laryngeal squamous cell carcinoma (LSCC) |
| spellingShingle | Zhao-Qu Li Lan Zou Tian-Run Liu An-Kui Yang Prognostic value of body mass index before treatment for laryngeal squamous cell carcinoma Cancer Biology & Medicine Prognosis nutrition body mass index (BMI) laryngeal squamous cell carcinoma (LSCC) |
| title | Prognostic value of body mass index before treatment for laryngeal squamous cell carcinoma |
| title_full | Prognostic value of body mass index before treatment for laryngeal squamous cell carcinoma |
| title_fullStr | Prognostic value of body mass index before treatment for laryngeal squamous cell carcinoma |
| title_full_unstemmed | Prognostic value of body mass index before treatment for laryngeal squamous cell carcinoma |
| title_short | Prognostic value of body mass index before treatment for laryngeal squamous cell carcinoma |
| title_sort | prognostic value of body mass index before treatment for laryngeal squamous cell carcinoma |
| topic | Prognosis nutrition body mass index (BMI) laryngeal squamous cell carcinoma (LSCC) |
| url | http://www.cancerbiomed.org/index.php/cocr/article/view/893 |
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