Pancreatic ductal adenocarcinoma in colonic wall: metastatic disease or cancerized pancreatic ectopic tissue?
Abstract We describe two unusual cases of cancerized ectopic pancreatic parenchyma within the wall of the left colon. Although the morphology of the neoplastic cells and their immunoprofile were consistent with pancreatic ductal adenocarcinoma, the detection of small foci of regular ectopic pancreat...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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SpringerOpen
2020-04-01
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| Series: | Surgical Case Reports |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s40792-020-00846-5 |
| _version_ | 1811268159104090112 |
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| author | Graziana Gallo Alessandro Mangogna Gianrocco Manco Stefania Caramaschi Tiziana Salviato |
| author_facet | Graziana Gallo Alessandro Mangogna Gianrocco Manco Stefania Caramaschi Tiziana Salviato |
| author_sort | Graziana Gallo |
| collection | DOAJ |
| description | Abstract We describe two unusual cases of cancerized ectopic pancreatic parenchyma within the wall of the left colon. Although the morphology of the neoplastic cells and their immunoprofile were consistent with pancreatic ductal adenocarcinoma, the detection of small foci of regular ectopic pancreatic tissue close to dysplastic glands at the periphery of the cancerized mass represented the key diagnostic features. A careful histological examination of surgical samples represents the correct approach to the diagnosis of this rare disease, mostly when total-body CT scan evaluation confirms the lack of bilio-pancreatic masses. |
| first_indexed | 2024-04-12T21:16:49Z |
| format | Article |
| id | doaj.art-1bfc092db0f1486c83019d31c812b2f5 |
| institution | Directory Open Access Journal |
| issn | 2198-7793 |
| language | English |
| last_indexed | 2024-04-12T21:16:49Z |
| publishDate | 2020-04-01 |
| publisher | SpringerOpen |
| record_format | Article |
| series | Surgical Case Reports |
| spelling | doaj.art-1bfc092db0f1486c83019d31c812b2f52022-12-22T03:16:24ZengSpringerOpenSurgical Case Reports2198-77932020-04-01611310.1186/s40792-020-00846-5Pancreatic ductal adenocarcinoma in colonic wall: metastatic disease or cancerized pancreatic ectopic tissue?Graziana Gallo0Alessandro Mangogna1Gianrocco Manco2Stefania Caramaschi3Tiziana Salviato4Department of Diagnostic, Clinic and Public Health Medicine, University of Modena and Reggio EmiliaDepartment of Medical, Surgical and Health Science, University of Trieste, Cattinara HospitalDepartment of Surgery, University of ModenaDepartment of Diagnostic, Clinic and Public Health Medicine, University of Modena and Reggio EmiliaDepartment of Diagnostic, Clinic and Public Health Medicine, University of Modena and Reggio EmiliaAbstract We describe two unusual cases of cancerized ectopic pancreatic parenchyma within the wall of the left colon. Although the morphology of the neoplastic cells and their immunoprofile were consistent with pancreatic ductal adenocarcinoma, the detection of small foci of regular ectopic pancreatic tissue close to dysplastic glands at the periphery of the cancerized mass represented the key diagnostic features. A careful histological examination of surgical samples represents the correct approach to the diagnosis of this rare disease, mostly when total-body CT scan evaluation confirms the lack of bilio-pancreatic masses.http://link.springer.com/article/10.1186/s40792-020-00846-5Ectopic pancreasColonAdenocarcinoma |
| spellingShingle | Graziana Gallo Alessandro Mangogna Gianrocco Manco Stefania Caramaschi Tiziana Salviato Pancreatic ductal adenocarcinoma in colonic wall: metastatic disease or cancerized pancreatic ectopic tissue? Surgical Case Reports Ectopic pancreas Colon Adenocarcinoma |
| title | Pancreatic ductal adenocarcinoma in colonic wall: metastatic disease or cancerized pancreatic ectopic tissue? |
| title_full | Pancreatic ductal adenocarcinoma in colonic wall: metastatic disease or cancerized pancreatic ectopic tissue? |
| title_fullStr | Pancreatic ductal adenocarcinoma in colonic wall: metastatic disease or cancerized pancreatic ectopic tissue? |
| title_full_unstemmed | Pancreatic ductal adenocarcinoma in colonic wall: metastatic disease or cancerized pancreatic ectopic tissue? |
| title_short | Pancreatic ductal adenocarcinoma in colonic wall: metastatic disease or cancerized pancreatic ectopic tissue? |
| title_sort | pancreatic ductal adenocarcinoma in colonic wall metastatic disease or cancerized pancreatic ectopic tissue |
| topic | Ectopic pancreas Colon Adenocarcinoma |
| url | http://link.springer.com/article/10.1186/s40792-020-00846-5 |
| work_keys_str_mv | AT grazianagallo pancreaticductaladenocarcinomaincolonicwallmetastaticdiseaseorcancerizedpancreaticectopictissue AT alessandromangogna pancreaticductaladenocarcinomaincolonicwallmetastaticdiseaseorcancerizedpancreaticectopictissue AT gianroccomanco pancreaticductaladenocarcinomaincolonicwallmetastaticdiseaseorcancerizedpancreaticectopictissue AT stefaniacaramaschi pancreaticductaladenocarcinomaincolonicwallmetastaticdiseaseorcancerizedpancreaticectopictissue AT tizianasalviato pancreaticductaladenocarcinomaincolonicwallmetastaticdiseaseorcancerizedpancreaticectopictissue |