Targeted micelles with chemotherapeutics and gene drugs to inhibit the G1/S and G2/M mitotic cycle of prostate cancer

Targeted micelles with chemotherapeutics and gene drugs to inhibit the G1/S and G2/M mitotic cycle of prostate cancer

Abstract Background Chemotherapy and gene therapy are used in clinical practice for the treatment of castration-resistant prostate cancer. However, the poor efficiency of drug delivery and serious systemic side effects remain an obstacle to wider application of these drugs. Herein, we report newly d...

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Bibliographic Details
Main Authors: Yiran Zhang, Yanming Wang, Li Meng, Qingqing Huang, Yueqi Zhu, Wenguo Cui, Yingsheng Cheng, Ranlu Liu
Format: Article
Language:English
Published: BMC 2021-01-01
Series:Journal of Nanobiotechnology
Subjects:
Micelles
Targeted ligand
EPR
Prostate cancer
Gene therapy
Online Access:https://doi.org/10.1186/s12951-020-00756-6

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