Use of Arsenic Trioxide as an Antivascular and Thermosensitizing Agent in Solid Tumors

Use of Arsenic Trioxide as an Antivascular and Thermosensitizing Agent in Solid Tumors

Arsenic trioxide, As2O3 (ATO), has been found to be an effective chemotherapy drug for acute promyelocytic leukemia but its effect on solid tumors has not been fully explored. In the present report, we describe our observation that ATO is a potent antivascular agent and that it markedly enhances the...

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Bibliographic Details
Main Authors: Robert J. Griffin, Sang H. Lee, Kelly L. Rood, Michael J. Stewart, John C. Lyons, Young S. Lew, Heonjoo Park, Chang W. Song
Format: Article
Language:English
Published: Elsevier 2000-01-01
Series:Neoplasia: An International Journal for Oncology Research
Subjects:
arsenic trioxide
tumor perfusion
adhesion molecules
thermosensitization
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558600800469

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