Development of three-dimensional canine hepatic tumor model based on computed tomographic angiography for simulation of transarterial embolization
IntroductionTransarterial embolization (TAE) is one of the treatment options for liver masses that are not suitable for surgery and they have been applied in veterinary medicine for about 20 years, but surgical resection is considered as the first treatment option, and only a few case reports and ar...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2024-01-01
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| Series: | Frontiers in Veterinary Science |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fvets.2023.1280028/full |
| _version_ | 1797339129253462016 |
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| author | Miju Oh Jiyoung Ban Yooyoung Lee Minju Lee Sojin Kim Uhjin Kim Jiwoon Park Jaepung Han Jinhwa Chang Byungjin Kim Hyeongrok Yun Namsoon Lee Dongwoo Chang |
| author_facet | Miju Oh Jiyoung Ban Yooyoung Lee Minju Lee Sojin Kim Uhjin Kim Jiwoon Park Jaepung Han Jinhwa Chang Byungjin Kim Hyeongrok Yun Namsoon Lee Dongwoo Chang |
| author_sort | Miju Oh |
| collection | DOAJ |
| description | IntroductionTransarterial embolization (TAE) is one of the treatment options for liver masses that are not suitable for surgery and they have been applied in veterinary medicine for about 20 years, but surgical resection is considered as the first treatment option, and only a few case reports and articles about TAE in dogs have been published. Although understanding of vascular anatomy for the procedure is important, previous studies lack of the information about hepatic artery anatomy in small and toy-breed dogs. Due to the introduction of 3D print in veterinary medicine, it is now possible to make 3D models for preoperative planning. The purpose of this study is to understand the hepatic arterial vascular structure of various sizes and breeds of dogs, and to develop 3D-printed canine artery models with and without hepatic tumors to simulate TAE procedure.MethodsCT images of a total of 84 dogs with normal hepatic arteries were analyzed, and the mean value and standard deviation of body weight, celiac artery size, and hepatic artery size were 6.47 ± 4.44 kg, 3.28 ± 0.77 mm, and 2.14 ± 0.43 mm, respectively.ResultsIt was established that type 2-2-1, which has two separate hepatic branches—the right medial and left branch and the right lateral branch that runs to the right lateral lobe and caudate process—is the most prevalent of the hepatic artery branch types, as it was in the previous study. The review of 65 CT images of dogs with hepatic tumors showed that 44.6% (29/65) had multifocal lesions in multiple lobes, for which TAE can be recommended.DiscussionBased on the result, a 3D model of the normal canine hepatic artery and the hepatic tumor was made using one representative case from each group, and despite the models having some limitations in reflecting the exact tactile and velocity of blood vessels, TAE procedure was successfully simulated using both models. |
| first_indexed | 2024-03-08T09:41:27Z |
| format | Article |
| id | doaj.art-1c0a6700defb44b599b6e68fd6d05b35 |
| institution | Directory Open Access Journal |
| issn | 2297-1769 |
| language | English |
| last_indexed | 2024-03-08T09:41:27Z |
| publishDate | 2024-01-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Veterinary Science |
| spelling | doaj.art-1c0a6700defb44b599b6e68fd6d05b352024-01-30T04:23:31ZengFrontiers Media S.A.Frontiers in Veterinary Science2297-17692024-01-011010.3389/fvets.2023.12800281280028Development of three-dimensional canine hepatic tumor model based on computed tomographic angiography for simulation of transarterial embolizationMiju Oh0Jiyoung Ban1Yooyoung Lee2Minju Lee3Sojin Kim4Uhjin Kim5Jiwoon Park6Jaepung Han7Jinhwa Chang8Byungjin Kim9Hyeongrok Yun10Namsoon Lee11Dongwoo Chang12Section of Veterinary Imaging, Veterinary Medical Center, College of Veterinary Medicine, Chungbuk National University, Cheongju, Republic of KoreaSection of Veterinary Imaging, Veterinary Medical Center, College of Veterinary Medicine, Chungbuk National University, Cheongju, Republic of KoreaSection of Veterinary Imaging, Veterinary Medical Center, College of Veterinary Medicine, Chungbuk National University, Cheongju, Republic of KoreaSection of Veterinary Imaging, Veterinary Medical Center, College of Veterinary Medicine, Chungbuk National University, Cheongju, Republic of KoreaSection of Veterinary Imaging, Veterinary Medical Center, College of Veterinary Medicine, Chungbuk National University, Cheongju, Republic of KoreaSection of Veterinary Imaging, Veterinary Medical Center, College of Veterinary Medicine, Chungbuk National University, Cheongju, Republic of KoreaSection of Veterinary Imaging, Veterinary Medical Center, College of Veterinary Medicine, Chungbuk National University, Cheongju, Republic of KoreaSection of Veterinary Imaging, Veterinary Medical Center, College of Veterinary Medicine, Chungbuk National University, Cheongju, Republic of KoreaKorea Animal Medical Center, Cheongju, Republic of KoreaBon Animal Medical Center, Suwon, Republic of KoreaSKY Animal Medical Center, Cheonan, Republic of KoreaSection of Veterinary Imaging, Veterinary Medical Center, College of Veterinary Medicine, Chungbuk National University, Cheongju, Republic of KoreaSection of Veterinary Imaging, Veterinary Medical Center, College of Veterinary Medicine, Chungbuk National University, Cheongju, Republic of KoreaIntroductionTransarterial embolization (TAE) is one of the treatment options for liver masses that are not suitable for surgery and they have been applied in veterinary medicine for about 20 years, but surgical resection is considered as the first treatment option, and only a few case reports and articles about TAE in dogs have been published. Although understanding of vascular anatomy for the procedure is important, previous studies lack of the information about hepatic artery anatomy in small and toy-breed dogs. Due to the introduction of 3D print in veterinary medicine, it is now possible to make 3D models for preoperative planning. The purpose of this study is to understand the hepatic arterial vascular structure of various sizes and breeds of dogs, and to develop 3D-printed canine artery models with and without hepatic tumors to simulate TAE procedure.MethodsCT images of a total of 84 dogs with normal hepatic arteries were analyzed, and the mean value and standard deviation of body weight, celiac artery size, and hepatic artery size were 6.47 ± 4.44 kg, 3.28 ± 0.77 mm, and 2.14 ± 0.43 mm, respectively.ResultsIt was established that type 2-2-1, which has two separate hepatic branches—the right medial and left branch and the right lateral branch that runs to the right lateral lobe and caudate process—is the most prevalent of the hepatic artery branch types, as it was in the previous study. The review of 65 CT images of dogs with hepatic tumors showed that 44.6% (29/65) had multifocal lesions in multiple lobes, for which TAE can be recommended.DiscussionBased on the result, a 3D model of the normal canine hepatic artery and the hepatic tumor was made using one representative case from each group, and despite the models having some limitations in reflecting the exact tactile and velocity of blood vessels, TAE procedure was successfully simulated using both models.https://www.frontiersin.org/articles/10.3389/fvets.2023.1280028/fullhepatocellular carcinomatransarterial embolization3D-printed canine hepatic artery modeltransarterial chemoembolizationintervention |
| spellingShingle | Miju Oh Jiyoung Ban Yooyoung Lee Minju Lee Sojin Kim Uhjin Kim Jiwoon Park Jaepung Han Jinhwa Chang Byungjin Kim Hyeongrok Yun Namsoon Lee Dongwoo Chang Development of three-dimensional canine hepatic tumor model based on computed tomographic angiography for simulation of transarterial embolization Frontiers in Veterinary Science hepatocellular carcinoma transarterial embolization 3D-printed canine hepatic artery model transarterial chemoembolization intervention |
| title | Development of three-dimensional canine hepatic tumor model based on computed tomographic angiography for simulation of transarterial embolization |
| title_full | Development of three-dimensional canine hepatic tumor model based on computed tomographic angiography for simulation of transarterial embolization |
| title_fullStr | Development of three-dimensional canine hepatic tumor model based on computed tomographic angiography for simulation of transarterial embolization |
| title_full_unstemmed | Development of three-dimensional canine hepatic tumor model based on computed tomographic angiography for simulation of transarterial embolization |
| title_short | Development of three-dimensional canine hepatic tumor model based on computed tomographic angiography for simulation of transarterial embolization |
| title_sort | development of three dimensional canine hepatic tumor model based on computed tomographic angiography for simulation of transarterial embolization |
| topic | hepatocellular carcinoma transarterial embolization 3D-printed canine hepatic artery model transarterial chemoembolization intervention |
| url | https://www.frontiersin.org/articles/10.3389/fvets.2023.1280028/full |
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