Factors Associated with White Fat Browning: New Regulators of Lipid Metabolism
Mammalian adipose tissue can be divided into white and brown adipose tissue based on its colour, location, and cellular structure. Certain conditions, such as sympathetic nerve excitement, can induce the white adipose adipocytes into a new type of adipocytes, known as beige adipocytes. The process,...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-07-01
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| Series: | International Journal of Molecular Sciences |
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| Online Access: | https://www.mdpi.com/1422-0067/23/14/7641 |
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| author | Peiwen Zhang Yuxu He Shuang Wu Xinrong Li Xutao Lin Mailin Gan Lei Chen Ye Zhao Lili Niu Shunhua Zhang Xuewei Li Li Zhu Linyuan Shen |
| author_facet | Peiwen Zhang Yuxu He Shuang Wu Xinrong Li Xutao Lin Mailin Gan Lei Chen Ye Zhao Lili Niu Shunhua Zhang Xuewei Li Li Zhu Linyuan Shen |
| author_sort | Peiwen Zhang |
| collection | DOAJ |
| description | Mammalian adipose tissue can be divided into white and brown adipose tissue based on its colour, location, and cellular structure. Certain conditions, such as sympathetic nerve excitement, can induce the white adipose adipocytes into a new type of adipocytes, known as beige adipocytes. The process, leading to the conversion of white adipocytes into beige adipocytes, is called white fat browning. The dynamic balance between white and beige adipocytes is closely related to the body’s metabolic homeostasis. Studying the signal transduction pathways of the white fat browning might provide novel ideas for the treatment of obesity and alleviation of obesity-related glucose and lipid metabolism disorders. This article aimed to provide an overview of recent advances in understanding white fat browning and the role of BAT in lipid metabolism. |
| first_indexed | 2024-03-09T13:42:57Z |
| format | Article |
| id | doaj.art-1c0e1b3135aa4d379c8c2e01062d820a |
| institution | Directory Open Access Journal |
| issn | 1661-6596 1422-0067 |
| language | English |
| last_indexed | 2024-03-09T13:42:57Z |
| publishDate | 2022-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | International Journal of Molecular Sciences |
| spelling | doaj.art-1c0e1b3135aa4d379c8c2e01062d820a2023-11-30T21:04:26ZengMDPI AGInternational Journal of Molecular Sciences1661-65961422-00672022-07-012314764110.3390/ijms23147641Factors Associated with White Fat Browning: New Regulators of Lipid MetabolismPeiwen Zhang0Yuxu He1Shuang Wu2Xinrong Li3Xutao Lin4Mailin Gan5Lei Chen6Ye Zhao7Lili Niu8Shunhua Zhang9Xuewei Li10Li Zhu11Linyuan Shen12College of Animal Science and Technology, Sichuan Agricultural University, Chengdu 611130, ChinaCollege of Animal Science and Technology, Sichuan Agricultural University, Chengdu 611130, ChinaCollege of Animal Science and Technology, Sichuan Agricultural University, Chengdu 611130, ChinaCollege of Animal Science and Technology, Sichuan Agricultural University, Chengdu 611130, ChinaCollege of Animal Science and Technology, Sichuan Agricultural University, Chengdu 611130, ChinaCollege of Animal Science and Technology, Sichuan Agricultural University, Chengdu 611130, ChinaCollege of Animal Science and Technology, Sichuan Agricultural University, Chengdu 611130, ChinaCollege of Animal Science and Technology, Sichuan Agricultural University, Chengdu 611130, ChinaCollege of Animal Science and Technology, Sichuan Agricultural University, Chengdu 611130, ChinaCollege of Animal Science and Technology, Sichuan Agricultural University, Chengdu 611130, ChinaCollege of Animal Science and Technology, Sichuan Agricultural University, Chengdu 611130, ChinaCollege of Animal Science and Technology, Sichuan Agricultural University, Chengdu 611130, ChinaCollege of Animal Science and Technology, Sichuan Agricultural University, Chengdu 611130, ChinaMammalian adipose tissue can be divided into white and brown adipose tissue based on its colour, location, and cellular structure. Certain conditions, such as sympathetic nerve excitement, can induce the white adipose adipocytes into a new type of adipocytes, known as beige adipocytes. The process, leading to the conversion of white adipocytes into beige adipocytes, is called white fat browning. The dynamic balance between white and beige adipocytes is closely related to the body’s metabolic homeostasis. Studying the signal transduction pathways of the white fat browning might provide novel ideas for the treatment of obesity and alleviation of obesity-related glucose and lipid metabolism disorders. This article aimed to provide an overview of recent advances in understanding white fat browning and the role of BAT in lipid metabolism.https://www.mdpi.com/1422-0067/23/14/7641white fatbrown fatobesityepigeneticfat thermogenesis |
| spellingShingle | Peiwen Zhang Yuxu He Shuang Wu Xinrong Li Xutao Lin Mailin Gan Lei Chen Ye Zhao Lili Niu Shunhua Zhang Xuewei Li Li Zhu Linyuan Shen Factors Associated with White Fat Browning: New Regulators of Lipid Metabolism International Journal of Molecular Sciences white fat brown fat obesity epigenetic fat thermogenesis |
| title | Factors Associated with White Fat Browning: New Regulators of Lipid Metabolism |
| title_full | Factors Associated with White Fat Browning: New Regulators of Lipid Metabolism |
| title_fullStr | Factors Associated with White Fat Browning: New Regulators of Lipid Metabolism |
| title_full_unstemmed | Factors Associated with White Fat Browning: New Regulators of Lipid Metabolism |
| title_short | Factors Associated with White Fat Browning: New Regulators of Lipid Metabolism |
| title_sort | factors associated with white fat browning new regulators of lipid metabolism |
| topic | white fat brown fat obesity epigenetic fat thermogenesis |
| url | https://www.mdpi.com/1422-0067/23/14/7641 |
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