Comprehensive analysis of pyroptosis regulators and tumor immune microenvironment in clear cell renal cell carcinoma

Comprehensive analysis of pyroptosis regulators and tumor immune microenvironment in clear cell renal cell carcinoma

Abstract Background Increasing evidence has indicated that pyroptosis could regulate the tumor immune microenvironment (TIME) to affect the tumor development. As a highly immunogenic tumor, clear cell renal cell carcinoma (ccRCC) can benefit from immunotherapy, but related research on pyroptosis in...

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Bibliographic Details
Main Authors: Yan Zhang, Xianwu Chen, Qinghe Fu, Feifan Wang, Xuejian Zhou, Jiayong Xiang, Ning He, Zhenghui Hu, Xiaodong Jin
Format: Article
Language:English
Published: BMC 2021-12-01
Series:Cancer Cell International
Subjects:
Clear cell renal cell carcinoma
Pyroptosis
Tumor immune microenvironment
Immune checkpoints
Immunotherapy
Online Access:https://doi.org/10.1186/s12935-021-02384-y

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