Frequency of Fibromyalgia in Hypothyroidism: A Cross-Sectional Study
Background and purpose: Fibromyalgia is a syndrome characterized by chronic musculoskeletal pain, tenderness, and other physical symptoms. We determined the frequency of Fibromyalgia in hypothyroid patients and the relationship between FM symptoms and hypothyroid status. Materials and methods: The c...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Mazandaran University of Medical Sciences
2023-12-01
|
| Series: | Journal of Mazandaran University of Medical Sciences |
| Subjects: | |
| Online Access: | http://jmums.mazums.ac.ir/article-1-20233-en.pdf |
| _version_ | 1797359811892871168 |
|---|---|
| author | Maryam Mobini Sajedehsadat Naghibi Zahra Kashi Reza Ali Mohammadpour Mehrnoush Sohrab |
| author_facet | Maryam Mobini Sajedehsadat Naghibi Zahra Kashi Reza Ali Mohammadpour Mehrnoush Sohrab |
| author_sort | Maryam Mobini |
| collection | DOAJ |
| description | Background and purpose: Fibromyalgia is a syndrome characterized by chronic musculoskeletal pain, tenderness, and other physical symptoms. We determined the frequency of Fibromyalgia in hypothyroid patients and the relationship between FM symptoms and hypothyroid status.
Materials and methods: The current study is a cross-sectional descriptive study investigating the prevalence and demographic characteristics of fibromyalgia in hypothyroid patients referred to University clinic in Sari in 1401-1402. Ninety-one hypothyroid patients were included in the study. The sampling method was convenience sampling. The sociodemographic features and the clinical features of hypothyroid patients were recorded. Thyroid tests included T4, TSH, and Anti Tpo Ab. Patients were examined for Fibromyalgia using American College Rheumatology (ACR) criteria for FM 2010 and 1990. For the patients who were classified as FM, the FIQR questionnaire was completed. To analyze the data, descriptive statistics indicators such as central and dispersion indicators and calculation of ratios were used, and to check the relationship between qualitative variables, chi-square test and quantitative variable comparison in different groups were used by t-tests and ANOVA in SPSS-25 software was used.
Results: The mean age and duration of hypothyroidism were 48.35 ± 13.8 and 9.84± 6.6 years respectively. The frequency of fibromyalgia in hypothyroid patients was 7(8%) patients based on ACR 2010 criteria. In patients with hypothyroidism and fibromyalgia, 6 patients (85.7%) were positive for Anti Tpo Ab, while in patients with hypothyroidism without fibromyalgia, 29 patients (34.5%) had this antibody (P=0.007).
Conclusion: It seems that Anti Tpo Ab is more important than thyroid dysfunction, and it is suggested to check this antibody in fibromyalgia patients in addition to thyroid function tests. |
| first_indexed | 2024-03-08T15:29:10Z |
| format | Article |
| id | doaj.art-1c113481e67549149ebef321a0a2418e |
| institution | Directory Open Access Journal |
| issn | 1735-9260 1735-9279 |
| language | English |
| last_indexed | 2024-03-08T15:29:10Z |
| publishDate | 2023-12-01 |
| publisher | Mazandaran University of Medical Sciences |
| record_format | Article |
| series | Journal of Mazandaran University of Medical Sciences |
| spelling | doaj.art-1c113481e67549149ebef321a0a2418e2024-01-10T06:52:06ZengMazandaran University of Medical SciencesJournal of Mazandaran University of Medical Sciences1735-92601735-92792023-12-01332287683Frequency of Fibromyalgia in Hypothyroidism: A Cross-Sectional StudyMaryam Mobini0Sajedehsadat Naghibi1Zahra Kashi2Reza Ali Mohammadpour3Mehrnoush Sohrab4 Professor, Department of Internal Medicine, Diabetes Research Center, Imam Khomeini Hospital, Mazandaran University of Medical Sciences, Sari, Iran Internist, Mazandaran University of Medical Sciences, Sari, Iran Professor, Department of Internal Medicine, Diabetes Research Center, Imam Khomeini Hospital, Mazandaran University of Medical Sciences, Sari, Iran Professor, Department of Biostatistics, Faculty of Health, IMazandaran University of Medical Sciences, Sari, Iran Assistant Professor, Department of Internal Medicine, Diabetes Research Center, Imam Khomeini Hospital, Mazandaran University of Medical Sciences, Sari, Iran Background and purpose: Fibromyalgia is a syndrome characterized by chronic musculoskeletal pain, tenderness, and other physical symptoms. We determined the frequency of Fibromyalgia in hypothyroid patients and the relationship between FM symptoms and hypothyroid status. Materials and methods: The current study is a cross-sectional descriptive study investigating the prevalence and demographic characteristics of fibromyalgia in hypothyroid patients referred to University clinic in Sari in 1401-1402. Ninety-one hypothyroid patients were included in the study. The sampling method was convenience sampling. The sociodemographic features and the clinical features of hypothyroid patients were recorded. Thyroid tests included T4, TSH, and Anti Tpo Ab. Patients were examined for Fibromyalgia using American College Rheumatology (ACR) criteria for FM 2010 and 1990. For the patients who were classified as FM, the FIQR questionnaire was completed. To analyze the data, descriptive statistics indicators such as central and dispersion indicators and calculation of ratios were used, and to check the relationship between qualitative variables, chi-square test and quantitative variable comparison in different groups were used by t-tests and ANOVA in SPSS-25 software was used. Results: The mean age and duration of hypothyroidism were 48.35 ± 13.8 and 9.84± 6.6 years respectively. The frequency of fibromyalgia in hypothyroid patients was 7(8%) patients based on ACR 2010 criteria. In patients with hypothyroidism and fibromyalgia, 6 patients (85.7%) were positive for Anti Tpo Ab, while in patients with hypothyroidism without fibromyalgia, 29 patients (34.5%) had this antibody (P=0.007). Conclusion: It seems that Anti Tpo Ab is more important than thyroid dysfunction, and it is suggested to check this antibody in fibromyalgia patients in addition to thyroid function tests.http://jmums.mazums.ac.ir/article-1-20233-en.pdffibromyalgiahypothyroidismanti tpo ab |
| spellingShingle | Maryam Mobini Sajedehsadat Naghibi Zahra Kashi Reza Ali Mohammadpour Mehrnoush Sohrab Frequency of Fibromyalgia in Hypothyroidism: A Cross-Sectional Study Journal of Mazandaran University of Medical Sciences fibromyalgia hypothyroidism anti tpo ab |
| title | Frequency of Fibromyalgia in Hypothyroidism: A Cross-Sectional Study |
| title_full | Frequency of Fibromyalgia in Hypothyroidism: A Cross-Sectional Study |
| title_fullStr | Frequency of Fibromyalgia in Hypothyroidism: A Cross-Sectional Study |
| title_full_unstemmed | Frequency of Fibromyalgia in Hypothyroidism: A Cross-Sectional Study |
| title_short | Frequency of Fibromyalgia in Hypothyroidism: A Cross-Sectional Study |
| title_sort | frequency of fibromyalgia in hypothyroidism a cross sectional study |
| topic | fibromyalgia hypothyroidism anti tpo ab |
| url | http://jmums.mazums.ac.ir/article-1-20233-en.pdf |
| work_keys_str_mv | AT maryammobini frequencyoffibromyalgiainhypothyroidismacrosssectionalstudy AT sajedehsadatnaghibi frequencyoffibromyalgiainhypothyroidismacrosssectionalstudy AT zahrakashi frequencyoffibromyalgiainhypothyroidismacrosssectionalstudy AT rezaalimohammadpour frequencyoffibromyalgiainhypothyroidismacrosssectionalstudy AT mehrnoushsohrab frequencyoffibromyalgiainhypothyroidismacrosssectionalstudy |