Divergent Rabies Virus Variant of Probable Bat Origin in 2 Gray Foxes, New Mexico, USA
In the Western Hemisphere, bat-associated rabies viruses (RABVs) have established independent transmission cycles in multiple mammal hosts, forming genetically distinct lineages. In New Mexico, USA, skunks, bats, and gray foxes are rabies reservoir hosts and represent a public health risk because o...
| Main Authors: | , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Centers for Disease Control and Prevention
2022-06-01
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| Series: | Emerging Infectious Diseases |
| Subjects: | |
| Online Access: | https://wwwnc.cdc.gov/eid/article/28/6/21-1718_article |
| _version_ | 1818231211688984576 |
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| author | Rene E. Condori Adam Aragon Mike Breckenridge Kendra Pesko Kerry Mower Paul Ettestad Sandra Melman Andres Velasco-Villa Lillian A. Orciari Pamela Yager Daniel G. Streicker Crystal M. Gigante Clint Morgan Ryan Wallace Yu Li |
| author_facet | Rene E. Condori Adam Aragon Mike Breckenridge Kendra Pesko Kerry Mower Paul Ettestad Sandra Melman Andres Velasco-Villa Lillian A. Orciari Pamela Yager Daniel G. Streicker Crystal M. Gigante Clint Morgan Ryan Wallace Yu Li |
| author_sort | Rene E. Condori |
| collection | DOAJ |
| description |
In the Western Hemisphere, bat-associated rabies viruses (RABVs) have established independent transmission cycles in multiple mammal hosts, forming genetically distinct lineages. In New Mexico, USA, skunks, bats, and gray foxes are rabies reservoir hosts and represent a public health risk because of encounters with humans. During 2015 and 2019, two previously undescribed RABVs were detected in 2 gray foxes (Urocyon cinereoargenteus) in Lincoln County, New Mexico. Phylogenetic analysis of the nucleoprotein gene indicated that the isolates are a novel RABV variant. These 2 cases probably represent repeated spillover events from an unknown bat reservoir to gray foxes. Molecular analysis of rabies cases across New Mexico identified that other cross-species transmission events were the result of viral variants previously known to be enzootic to New Mexico. Despite a robust rabies public health surveillance system in the United States, advances in testing and surveillance techniques continue to identify previously unrecognized zoonotic pathogens.
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| first_indexed | 2024-12-12T10:46:47Z |
| format | Article |
| id | doaj.art-1c13b2fc4b0f418cb3e7e3de48550959 |
| institution | Directory Open Access Journal |
| issn | 1080-6040 1080-6059 |
| language | English |
| last_indexed | 2024-12-12T10:46:47Z |
| publishDate | 2022-06-01 |
| publisher | Centers for Disease Control and Prevention |
| record_format | Article |
| series | Emerging Infectious Diseases |
| spelling | doaj.art-1c13b2fc4b0f418cb3e7e3de485509592022-12-22T00:26:52ZengCenters for Disease Control and PreventionEmerging Infectious Diseases1080-60401080-60592022-06-012861137114510.3201/eid2806.211718Divergent Rabies Virus Variant of Probable Bat Origin in 2 Gray Foxes, New Mexico, USARene E. CondoriAdam AragonMike BreckenridgeKendra PeskoKerry MowerPaul EttestadSandra MelmanAndres Velasco-VillaLillian A. OrciariPamela YagerDaniel G. StreickerCrystal M. GiganteClint MorganRyan WallaceYu Li In the Western Hemisphere, bat-associated rabies viruses (RABVs) have established independent transmission cycles in multiple mammal hosts, forming genetically distinct lineages. In New Mexico, USA, skunks, bats, and gray foxes are rabies reservoir hosts and represent a public health risk because of encounters with humans. During 2015 and 2019, two previously undescribed RABVs were detected in 2 gray foxes (Urocyon cinereoargenteus) in Lincoln County, New Mexico. Phylogenetic analysis of the nucleoprotein gene indicated that the isolates are a novel RABV variant. These 2 cases probably represent repeated spillover events from an unknown bat reservoir to gray foxes. Molecular analysis of rabies cases across New Mexico identified that other cross-species transmission events were the result of viral variants previously known to be enzootic to New Mexico. Despite a robust rabies public health surveillance system in the United States, advances in testing and surveillance techniques continue to identify previously unrecognized zoonotic pathogens. https://wwwnc.cdc.gov/eid/article/28/6/21-1718_articlerabiesrabies viruslyssavirusvirusesdivergent virus variantbats |
| spellingShingle | Rene E. Condori Adam Aragon Mike Breckenridge Kendra Pesko Kerry Mower Paul Ettestad Sandra Melman Andres Velasco-Villa Lillian A. Orciari Pamela Yager Daniel G. Streicker Crystal M. Gigante Clint Morgan Ryan Wallace Yu Li Divergent Rabies Virus Variant of Probable Bat Origin in 2 Gray Foxes, New Mexico, USA Emerging Infectious Diseases rabies rabies virus lyssavirus viruses divergent virus variant bats |
| title | Divergent Rabies Virus Variant of Probable Bat Origin in 2 Gray Foxes, New Mexico, USA |
| title_full | Divergent Rabies Virus Variant of Probable Bat Origin in 2 Gray Foxes, New Mexico, USA |
| title_fullStr | Divergent Rabies Virus Variant of Probable Bat Origin in 2 Gray Foxes, New Mexico, USA |
| title_full_unstemmed | Divergent Rabies Virus Variant of Probable Bat Origin in 2 Gray Foxes, New Mexico, USA |
| title_short | Divergent Rabies Virus Variant of Probable Bat Origin in 2 Gray Foxes, New Mexico, USA |
| title_sort | divergent rabies virus variant of probable bat origin in 2 gray foxes new mexico usa |
| topic | rabies rabies virus lyssavirus viruses divergent virus variant bats |
| url | https://wwwnc.cdc.gov/eid/article/28/6/21-1718_article |
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