Epidermal Growth Factor Receptor Kinase Inhibitor Ameliorates β-Amyloid Oligomer-Induced Alzheimer Disease in Swiss Albino Mice

Epidermal Growth Factor Receptor Kinase Inhibitor Ameliorates β-Amyloid Oligomer-Induced Alzheimer Disease in Swiss Albino Mice

Alzheimer’s disease (AD) is one of the major neurodegenerative disorders, and its incidence increases globally every year. Currently, available AD drugs symptomatically treat AD with multiple adverse effects. Gefitinib (GE) is an epidermal growth factor receptor (EGFR) kinase inhibitor. EGFR is the...

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Bibliographic Details
Main Authors: Jagadeesh Dhamodharan, Ganthimathy Sekhar, Arunachalam Muthuraman
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Molecules
Subjects:
acetylcholinesterase
donepezil
gefitinib
intracerebroventricular
Morris water maze
neurodegeneration
Online Access:https://www.mdpi.com/1420-3049/27/16/5182

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