Efficacy of 30% azelaic acid peel in the nonpharmacological treatment of facial acne
Background Acne is a common, chronic, inflammatory disease of the pilosebaceous unit. It has a significant impact on patient quality of life, especially when lesions occur on cosmetically sensitive areas. Chemical peeling is a well-known option in the treatment of acne vulgaris, but little is known...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Taylor & Francis Group
2021-04-01
|
| Series: | Journal of Dermatological Treatment |
| Subjects: | |
| Online Access: | http://dx.doi.org/10.1080/09546634.2019.1657222 |
| _version_ | 1797683653923307520 |
|---|---|
| author | Anna Szymańska Elzbieta Budzisz Anna Erkiert-Polguj |
| author_facet | Anna Szymańska Elzbieta Budzisz Anna Erkiert-Polguj |
| author_sort | Anna Szymańska |
| collection | DOAJ |
| description | Background Acne is a common, chronic, inflammatory disease of the pilosebaceous unit. It has a significant impact on patient quality of life, especially when lesions occur on cosmetically sensitive areas. Chemical peeling is a well-known option in the treatment of acne vulgaris, but little is known about azelaic acid (AZA) peels. Objectives To determine the efficacy of 30% AZA peel, in decreasing the amount of secreted sebum, and reducing acne lesions. Methods The study involved 35 women, with acne lesions on face skin. All the subjects underwent a series of six treatments, performed every 2 weeks. Results A series of treatments contributed to a statistically significant reduction in the amount of secreted sebum. Similarly, highly significant values determining the overall number of acne lesions and the severity of the disease according to the IGA scale were also changed. The procedure was well tolerated by all participants. Conclusions Peels with 30% AZA reduced acne lesions and normalized the activity of the sebaceous glands. The reduction of sebum allows us to believe that obtained good results in patients will be stable and long-lasting. |
| first_indexed | 2024-03-12T00:17:44Z |
| format | Article |
| id | doaj.art-1c1501f95a6040e5bb0d7320ca678700 |
| institution | Directory Open Access Journal |
| issn | 0954-6634 1471-1753 |
| language | English |
| last_indexed | 2024-03-12T00:17:44Z |
| publishDate | 2021-04-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Journal of Dermatological Treatment |
| spelling | doaj.art-1c1501f95a6040e5bb0d7320ca6787002023-09-15T14:23:03ZengTaylor & Francis GroupJournal of Dermatological Treatment0954-66341471-17532021-04-0132329129610.1080/09546634.2019.16572221657222Efficacy of 30% azelaic acid peel in the nonpharmacological treatment of facial acneAnna Szymańska0Elzbieta Budzisz1Anna Erkiert-Polguj2Department of Cosmetic Raw Materials Chemistry, Medical University of LodzDepartment of Cosmetic Raw Materials Chemistry, Medical University of LodzDepartment of Cosmetology and Aesthetic Dermatology, Medical University of LodzBackground Acne is a common, chronic, inflammatory disease of the pilosebaceous unit. It has a significant impact on patient quality of life, especially when lesions occur on cosmetically sensitive areas. Chemical peeling is a well-known option in the treatment of acne vulgaris, but little is known about azelaic acid (AZA) peels. Objectives To determine the efficacy of 30% AZA peel, in decreasing the amount of secreted sebum, and reducing acne lesions. Methods The study involved 35 women, with acne lesions on face skin. All the subjects underwent a series of six treatments, performed every 2 weeks. Results A series of treatments contributed to a statistically significant reduction in the amount of secreted sebum. Similarly, highly significant values determining the overall number of acne lesions and the severity of the disease according to the IGA scale were also changed. The procedure was well tolerated by all participants. Conclusions Peels with 30% AZA reduced acne lesions and normalized the activity of the sebaceous glands. The reduction of sebum allows us to believe that obtained good results in patients will be stable and long-lasting.http://dx.doi.org/10.1080/09546634.2019.1657222acneazelaic peeltreatmentpeel |
| spellingShingle | Anna Szymańska Elzbieta Budzisz Anna Erkiert-Polguj Efficacy of 30% azelaic acid peel in the nonpharmacological treatment of facial acne Journal of Dermatological Treatment acne azelaic peel treatment peel |
| title | Efficacy of 30% azelaic acid peel in the nonpharmacological treatment of facial acne |
| title_full | Efficacy of 30% azelaic acid peel in the nonpharmacological treatment of facial acne |
| title_fullStr | Efficacy of 30% azelaic acid peel in the nonpharmacological treatment of facial acne |
| title_full_unstemmed | Efficacy of 30% azelaic acid peel in the nonpharmacological treatment of facial acne |
| title_short | Efficacy of 30% azelaic acid peel in the nonpharmacological treatment of facial acne |
| title_sort | efficacy of 30 azelaic acid peel in the nonpharmacological treatment of facial acne |
| topic | acne azelaic peel treatment peel |
| url | http://dx.doi.org/10.1080/09546634.2019.1657222 |
| work_keys_str_mv | AT annaszymanska efficacyof30azelaicacidpeelinthenonpharmacologicaltreatmentoffacialacne AT elzbietabudzisz efficacyof30azelaicacidpeelinthenonpharmacologicaltreatmentoffacialacne AT annaerkiertpolguj efficacyof30azelaicacidpeelinthenonpharmacologicaltreatmentoffacialacne |