SARS-CoV-2 antibodies in adolescents living with perinatally acquired HIV

Data on children and adolescents with HIV and coronavirus disease 2019 (COVID-19) co-infection are limited. Clinical and antibody data related to COVID-19 infection in adolescents living with perinatally acquired HIV (ALPHIV) and originally enrolled in the Children with HIV Early Antiretroviral Ther...

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Main Authors: Lisa Frigati, Leonore Greybe, Shaun Barnabas, Mark Cotton, Helena Rabie
Format: Article
Language:English
Published: AOSIS 2024-03-01
Series:Southern African Journal of Infectious Diseases
Subjects:
Online Access:https://sajid.co.za/index.php/sajid/article/view/579
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author Lisa Frigati
Leonore Greybe
Shaun Barnabas
Mark Cotton
Helena Rabie
author_facet Lisa Frigati
Leonore Greybe
Shaun Barnabas
Mark Cotton
Helena Rabie
author_sort Lisa Frigati
collection DOAJ
description Data on children and adolescents with HIV and coronavirus disease 2019 (COVID-19) co-infection are limited. Clinical and antibody data related to COVID-19 infection in adolescents living with perinatally acquired HIV (ALPHIV) and originally enrolled in the Children with HIV Early Antiretroviral Therapy (CHER) study were collected. We present a descriptive analysis of 53 ALPHIV who were tested for anti-SARS-CoV-2 antibodies. Just over half (53%) of the adolescents tested had positive anti-SARS-CoV-2 antibodies with only one participant describing a prior history of possible symptomatic infection. Contribution: The study contributes to the understanding of SARS-CoV-2 infection and vaccination practices in HIV-positive adolescents.
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spelling doaj.art-1c186861743e4a71826c34ac9dc776352024-04-04T09:29:22ZengAOSISSouthern African Journal of Infectious Diseases2312-00532313-18102024-03-01391e1e310.4102/sajid.v39i1.579294SARS-CoV-2 antibodies in adolescents living with perinatally acquired HIVLisa Frigati0Leonore Greybe1Shaun Barnabas2Mark Cotton3Helena Rabie4Department of Paediatrics and Child Health, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape TownDepartment of Paediatrics and Child Health, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape TownDepartment of Paediatrics and Child Health, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape TownDepartment of Paediatrics and Child Health, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape TownDepartment of Paediatrics and Child Health, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape TownData on children and adolescents with HIV and coronavirus disease 2019 (COVID-19) co-infection are limited. Clinical and antibody data related to COVID-19 infection in adolescents living with perinatally acquired HIV (ALPHIV) and originally enrolled in the Children with HIV Early Antiretroviral Therapy (CHER) study were collected. We present a descriptive analysis of 53 ALPHIV who were tested for anti-SARS-CoV-2 antibodies. Just over half (53%) of the adolescents tested had positive anti-SARS-CoV-2 antibodies with only one participant describing a prior history of possible symptomatic infection. Contribution: The study contributes to the understanding of SARS-CoV-2 infection and vaccination practices in HIV-positive adolescents.https://sajid.co.za/index.php/sajid/article/view/579sars-cov2 antibodiesadolescentsadolescent hivperinatal hivcovid-19vaccination.
spellingShingle Lisa Frigati
Leonore Greybe
Shaun Barnabas
Mark Cotton
Helena Rabie
SARS-CoV-2 antibodies in adolescents living with perinatally acquired HIV
Southern African Journal of Infectious Diseases
sars-cov2 antibodies
adolescents
adolescent hiv
perinatal hiv
covid-19
vaccination.
title SARS-CoV-2 antibodies in adolescents living with perinatally acquired HIV
title_full SARS-CoV-2 antibodies in adolescents living with perinatally acquired HIV
title_fullStr SARS-CoV-2 antibodies in adolescents living with perinatally acquired HIV
title_full_unstemmed SARS-CoV-2 antibodies in adolescents living with perinatally acquired HIV
title_short SARS-CoV-2 antibodies in adolescents living with perinatally acquired HIV
title_sort sars cov 2 antibodies in adolescents living with perinatally acquired hiv
topic sars-cov2 antibodies
adolescents
adolescent hiv
perinatal hiv
covid-19
vaccination.
url https://sajid.co.za/index.php/sajid/article/view/579
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