Prevention of post-endoscopic retrograde cholangiopancreatography pancreatitis with rectal non-steroidal anti-inflammatory drugs
Acute pancreatitis is the most common and feared adverse event associated with performance of endoscopic retrograde cholangiopancreatography (ERCP). Unremitting effort has been made for over 40 years to minimize the frequency and severity of this complication. Recently, the use of rectal non-steroid...
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Format: | Article |
Language: | English |
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The Korean Association of Internal Medicine
2020-05-01
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Series: | The Korean Journal of Internal Medicine |
Subjects: | |
Online Access: | http://www.kjim.org/upload/pdf/kjim-2020-069.pdf |
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author | Tae Young Park Hyoung-Chul Oh Evan L. Fogel Glen A. Lehman |
author_facet | Tae Young Park Hyoung-Chul Oh Evan L. Fogel Glen A. Lehman |
author_sort | Tae Young Park |
collection | DOAJ |
description | Acute pancreatitis is the most common and feared adverse event associated with performance of endoscopic retrograde cholangiopancreatography (ERCP). Unremitting effort has been made for over 40 years to minimize the frequency and severity of this complication. Recently, the use of rectal non-steroidal anti-inflammatory drugs (NSAIDs) have opened a new era for its prevention. This review focuses on the role of NSAIDs in pancreatitis, the pharmacokinetics of these agents, and summarizes the results of clinical trials with rectal NSAIDs alone and combination regimens in the prevention of post-ERCP pancreatitis. |
first_indexed | 2024-12-16T14:33:05Z |
format | Article |
id | doaj.art-1c19051d8e474a108b40e5b384aa89b4 |
institution | Directory Open Access Journal |
issn | 1226-3303 2005-6648 |
language | English |
last_indexed | 2024-12-16T14:33:05Z |
publishDate | 2020-05-01 |
publisher | The Korean Association of Internal Medicine |
record_format | Article |
series | The Korean Journal of Internal Medicine |
spelling | doaj.art-1c19051d8e474a108b40e5b384aa89b42022-12-21T22:28:11ZengThe Korean Association of Internal MedicineThe Korean Journal of Internal Medicine1226-33032005-66482020-05-0135353554310.3904/kjim.2020.069170368Prevention of post-endoscopic retrograde cholangiopancreatography pancreatitis with rectal non-steroidal anti-inflammatory drugsTae Young Park0Hyoung-Chul Oh1Evan L. Fogel2Glen A. Lehman3 Department of Internal Medicine, Inje University Seoul Paik Hospital, Seoul, Korea Division of Gastroenterology, Chung-Ang University College of Medicine, Seoul, Korea Division of Gastroenterology and Hepatology, Indiana University School of Medicine, Indianapolis, IN, USA Division of Gastroenterology and Hepatology, Indiana University School of Medicine, Indianapolis, IN, USAAcute pancreatitis is the most common and feared adverse event associated with performance of endoscopic retrograde cholangiopancreatography (ERCP). Unremitting effort has been made for over 40 years to minimize the frequency and severity of this complication. Recently, the use of rectal non-steroidal anti-inflammatory drugs (NSAIDs) have opened a new era for its prevention. This review focuses on the role of NSAIDs in pancreatitis, the pharmacokinetics of these agents, and summarizes the results of clinical trials with rectal NSAIDs alone and combination regimens in the prevention of post-ERCP pancreatitis.http://www.kjim.org/upload/pdf/kjim-2020-069.pdfcholangiopancreatography, endoscopic retrogradepancreatitisanti-inflammatory agents, non-steroidal |
spellingShingle | Tae Young Park Hyoung-Chul Oh Evan L. Fogel Glen A. Lehman Prevention of post-endoscopic retrograde cholangiopancreatography pancreatitis with rectal non-steroidal anti-inflammatory drugs The Korean Journal of Internal Medicine cholangiopancreatography, endoscopic retrograde pancreatitis anti-inflammatory agents, non-steroidal |
title | Prevention of post-endoscopic retrograde cholangiopancreatography pancreatitis with rectal non-steroidal anti-inflammatory drugs |
title_full | Prevention of post-endoscopic retrograde cholangiopancreatography pancreatitis with rectal non-steroidal anti-inflammatory drugs |
title_fullStr | Prevention of post-endoscopic retrograde cholangiopancreatography pancreatitis with rectal non-steroidal anti-inflammatory drugs |
title_full_unstemmed | Prevention of post-endoscopic retrograde cholangiopancreatography pancreatitis with rectal non-steroidal anti-inflammatory drugs |
title_short | Prevention of post-endoscopic retrograde cholangiopancreatography pancreatitis with rectal non-steroidal anti-inflammatory drugs |
title_sort | prevention of post endoscopic retrograde cholangiopancreatography pancreatitis with rectal non steroidal anti inflammatory drugs |
topic | cholangiopancreatography, endoscopic retrograde pancreatitis anti-inflammatory agents, non-steroidal |
url | http://www.kjim.org/upload/pdf/kjim-2020-069.pdf |
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