Isolated recurrence of prostate cancer to the anterior urethra 5 years after radiation therapy
Introduction Primary or metastatic urethral tumors are extremely rare. However, treatment strategies differ between primary and metastatic tumors. Therefore, establishing an accurate diagnosis is critically needed for initiating timely and appropriate therapy. Case presentation We describe the case...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2022-01-01
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| Series: | IJU Case Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/iju5.12394 |
| _version_ | 1819172675096936448 |
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| author | Shinnosuke Fujiwara Masaru Ishida Eri Arai Yuto Baba Tadatsugu Anno Hiroaki Kobayashi Yasumasa Miyazaki |
| author_facet | Shinnosuke Fujiwara Masaru Ishida Eri Arai Yuto Baba Tadatsugu Anno Hiroaki Kobayashi Yasumasa Miyazaki |
| author_sort | Shinnosuke Fujiwara |
| collection | DOAJ |
| description | Introduction Primary or metastatic urethral tumors are extremely rare. However, treatment strategies differ between primary and metastatic tumors. Therefore, establishing an accurate diagnosis is critically needed for initiating timely and appropriate therapy. Case presentation We describe the case of a 79‐year‐old man with prostate cancer treated with radiotherapy and androgen deprivation therapy. He presented with macroscopic hematuria as a symptom of anterior urethral tumor at follow‐up. Endoscopic tumor resection was performed. Hematoxylin and eosin staining showed adenocarcinoma component. Immunohistochemical staining revealed presence of metastatic prostate cancer to the urethra. Conclusion Regarding urethral tumors diagnosis, urologists should consider the possibility of metastasis from prostate cancer and perform immunohistochemical examination for establishing accurate diagnosis. Furthermore, if androgen deprivation therapy fails to suppress symptoms, radiotherapy or urethrectomy might be considered. |
| first_indexed | 2024-12-22T20:10:57Z |
| format | Article |
| id | doaj.art-1c192788118a41f19b4872ba29fd0fc0 |
| institution | Directory Open Access Journal |
| issn | 2577-171X |
| language | English |
| last_indexed | 2024-12-22T20:10:57Z |
| publishDate | 2022-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | IJU Case Reports |
| spelling | doaj.art-1c192788118a41f19b4872ba29fd0fc02022-12-21T18:14:02ZengWileyIJU Case Reports2577-171X2022-01-0151586110.1002/iju5.12394Isolated recurrence of prostate cancer to the anterior urethra 5 years after radiation therapyShinnosuke Fujiwara0Masaru Ishida1Eri Arai2Yuto Baba3Tadatsugu Anno4Hiroaki Kobayashi5Yasumasa Miyazaki6Department of Urology Saiseikai Yokohamashi Tobu Hospital KanagawaJapanDepartment of Urology Saiseikai Yokohamashi Tobu Hospital KanagawaJapanDepartment of Pathology Keio University School of Medicine Tokyo JapanDepartment of Urology Saiseikai Yokohamashi Tobu Hospital KanagawaJapanDepartment of Urology Saiseikai Yokohamashi Tobu Hospital KanagawaJapanDepartment of Urology Saiseikai Yokohamashi Tobu Hospital KanagawaJapanDepartment of Urology Saiseikai Yokohamashi Tobu Hospital KanagawaJapanIntroduction Primary or metastatic urethral tumors are extremely rare. However, treatment strategies differ between primary and metastatic tumors. Therefore, establishing an accurate diagnosis is critically needed for initiating timely and appropriate therapy. Case presentation We describe the case of a 79‐year‐old man with prostate cancer treated with radiotherapy and androgen deprivation therapy. He presented with macroscopic hematuria as a symptom of anterior urethral tumor at follow‐up. Endoscopic tumor resection was performed. Hematoxylin and eosin staining showed adenocarcinoma component. Immunohistochemical staining revealed presence of metastatic prostate cancer to the urethra. Conclusion Regarding urethral tumors diagnosis, urologists should consider the possibility of metastasis from prostate cancer and perform immunohistochemical examination for establishing accurate diagnosis. Furthermore, if androgen deprivation therapy fails to suppress symptoms, radiotherapy or urethrectomy might be considered.https://doi.org/10.1002/iju5.12394adenocarcinomaandrogen antagonistslocal neoplasms recurrenceprostatic neoplasmsurethra |
| spellingShingle | Shinnosuke Fujiwara Masaru Ishida Eri Arai Yuto Baba Tadatsugu Anno Hiroaki Kobayashi Yasumasa Miyazaki Isolated recurrence of prostate cancer to the anterior urethra 5 years after radiation therapy IJU Case Reports adenocarcinoma androgen antagonists local neoplasms recurrence prostatic neoplasms urethra |
| title | Isolated recurrence of prostate cancer to the anterior urethra 5 years after radiation therapy |
| title_full | Isolated recurrence of prostate cancer to the anterior urethra 5 years after radiation therapy |
| title_fullStr | Isolated recurrence of prostate cancer to the anterior urethra 5 years after radiation therapy |
| title_full_unstemmed | Isolated recurrence of prostate cancer to the anterior urethra 5 years after radiation therapy |
| title_short | Isolated recurrence of prostate cancer to the anterior urethra 5 years after radiation therapy |
| title_sort | isolated recurrence of prostate cancer to the anterior urethra 5 years after radiation therapy |
| topic | adenocarcinoma androgen antagonists local neoplasms recurrence prostatic neoplasms urethra |
| url | https://doi.org/10.1002/iju5.12394 |
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