Efficacy of Dietary Supplementation with <i>Capsicum Annum</i> L on Performance, Hematology, Blood Biochemistry and Hepatic Antioxidant Status of Growing Rabbits
Animals fed with a high amount of a wide range of antioxidants in their diet are significantly protected against oxidative stress. Powerful antioxidant substances such as vitamin E, vitamin C, and carotenoids are present naturally in red-hot pepper (RHP). This study hypothesized that using RHP may p...
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MDPI AG
2020-11-01
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| Series: | Animals |
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| Online Access: | https://www.mdpi.com/2076-2615/10/11/2045 |
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| author | Hamada Elwan Mostafa Abdelhakeam Sally El-Shafei Atef Abd El-Rahman Zienhom Ismail Abdalrahman Zanouny Emad Shaker Salim S. Al-Rejaie Mohamed Mohany Shaaban Elnesr |
| author_facet | Hamada Elwan Mostafa Abdelhakeam Sally El-Shafei Atef Abd El-Rahman Zienhom Ismail Abdalrahman Zanouny Emad Shaker Salim S. Al-Rejaie Mohamed Mohany Shaaban Elnesr |
| author_sort | Hamada Elwan |
| collection | DOAJ |
| description | Animals fed with a high amount of a wide range of antioxidants in their diet are significantly protected against oxidative stress. Powerful antioxidant substances such as vitamin E, vitamin C, and carotenoids are present naturally in red-hot pepper (RHP). This study hypothesized that using RHP may provide protection against oxidative stress and enhance animal physiological responses. Thus, this study aimed to investigate the effect of feeding New Zealand white rabbits with RHP-supplemented diets on their physiological and biochemical responses. New Zealand White rabbits (age = 6 weeks, n = 48) were split equally into three groups (n = 16 in each group). One group was fed a basal diet only (control group), with the other two groups fed a basal diet along with 1 and 2% RHP. Mass spectrometric analysis for the RHP methanolic extract showed some phenolic compounds, such as p-coumaric, sinapinic acids, vanillic, and luteolin, as well as catechin and its isomers. Hepatic antioxidant enzymes (SOD, GSH, GSH-Px, and CAT) were significantly elevated (<i>p</i> < 0.05) by feeding rabbits diets supplemented with 1 or 2% RHP. The addition of RHP significantly enhanced immune-responses; phagocytic activity, chemotaxis, TIg, IgG, IgM, and IgA increased when growing rabbits were fed RHP compared with the control group. In conclusion, dietary supplementation of 1 or 2% RHP may play a role as an enhancer of growth and immune response in growing rabbits. |
| first_indexed | 2024-03-10T15:04:47Z |
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| institution | Directory Open Access Journal |
| issn | 2076-2615 |
| language | English |
| last_indexed | 2024-03-10T15:04:47Z |
| publishDate | 2020-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Animals |
| spelling | doaj.art-1c1a8dcbd9e748b2855e203210c5637f2023-11-20T19:52:40ZengMDPI AGAnimals2076-26152020-11-011011204510.3390/ani10112045Efficacy of Dietary Supplementation with <i>Capsicum Annum</i> L on Performance, Hematology, Blood Biochemistry and Hepatic Antioxidant Status of Growing RabbitsHamada Elwan0Mostafa Abdelhakeam1Sally El-Shafei2Atef Abd El-Rahman3Zienhom Ismail4Abdalrahman Zanouny5Emad Shaker6Salim S. Al-Rejaie7Mohamed Mohany8Shaaban Elnesr9Animal and Poultry Production Department, Faculty of Agriculture, Minia University, El-Minya 61519, EgyptAnimal and Poultry Production Department, Faculty of Agriculture, Minia University, El-Minya 61519, EgyptDepartment of Agricultural Chemistry, Faculty of Agriculture, Minia University, El-Minya 61519, EgyptDepartment of Agricultural Chemistry, Faculty of Agriculture, Minia University, El-Minya 61519, EgyptAnimal Production Department, Faculty of Agriculture, South Valley University, Qena 83523, EgyptAnimal and Poultry Production Department, Faculty of Agriculture, Minia University, El-Minya 61519, EgyptDepartment of Agricultural Chemistry, Faculty of Agriculture, Minia University, El-Minya 61519, EgyptDepartment of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh 11451, Saudi ArabiaDepartment of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh 11451, Saudi ArabiaPoultry Production Department, Faculty of Agriculture, Fayoum University, Fayoum 63514, EgyptAnimals fed with a high amount of a wide range of antioxidants in their diet are significantly protected against oxidative stress. Powerful antioxidant substances such as vitamin E, vitamin C, and carotenoids are present naturally in red-hot pepper (RHP). This study hypothesized that using RHP may provide protection against oxidative stress and enhance animal physiological responses. Thus, this study aimed to investigate the effect of feeding New Zealand white rabbits with RHP-supplemented diets on their physiological and biochemical responses. New Zealand White rabbits (age = 6 weeks, n = 48) were split equally into three groups (n = 16 in each group). One group was fed a basal diet only (control group), with the other two groups fed a basal diet along with 1 and 2% RHP. Mass spectrometric analysis for the RHP methanolic extract showed some phenolic compounds, such as p-coumaric, sinapinic acids, vanillic, and luteolin, as well as catechin and its isomers. Hepatic antioxidant enzymes (SOD, GSH, GSH-Px, and CAT) were significantly elevated (<i>p</i> < 0.05) by feeding rabbits diets supplemented with 1 or 2% RHP. The addition of RHP significantly enhanced immune-responses; phagocytic activity, chemotaxis, TIg, IgG, IgM, and IgA increased when growing rabbits were fed RHP compared with the control group. In conclusion, dietary supplementation of 1 or 2% RHP may play a role as an enhancer of growth and immune response in growing rabbits.https://www.mdpi.com/2076-2615/10/11/2045red hot pepperrabbitsMass detectionantioxidantsoxidative stress |
| spellingShingle | Hamada Elwan Mostafa Abdelhakeam Sally El-Shafei Atef Abd El-Rahman Zienhom Ismail Abdalrahman Zanouny Emad Shaker Salim S. Al-Rejaie Mohamed Mohany Shaaban Elnesr Efficacy of Dietary Supplementation with <i>Capsicum Annum</i> L on Performance, Hematology, Blood Biochemistry and Hepatic Antioxidant Status of Growing Rabbits Animals red hot pepper rabbits Mass detection antioxidants oxidative stress |
| title | Efficacy of Dietary Supplementation with <i>Capsicum Annum</i> L on Performance, Hematology, Blood Biochemistry and Hepatic Antioxidant Status of Growing Rabbits |
| title_full | Efficacy of Dietary Supplementation with <i>Capsicum Annum</i> L on Performance, Hematology, Blood Biochemistry and Hepatic Antioxidant Status of Growing Rabbits |
| title_fullStr | Efficacy of Dietary Supplementation with <i>Capsicum Annum</i> L on Performance, Hematology, Blood Biochemistry and Hepatic Antioxidant Status of Growing Rabbits |
| title_full_unstemmed | Efficacy of Dietary Supplementation with <i>Capsicum Annum</i> L on Performance, Hematology, Blood Biochemistry and Hepatic Antioxidant Status of Growing Rabbits |
| title_short | Efficacy of Dietary Supplementation with <i>Capsicum Annum</i> L on Performance, Hematology, Blood Biochemistry and Hepatic Antioxidant Status of Growing Rabbits |
| title_sort | efficacy of dietary supplementation with i capsicum annum i l on performance hematology blood biochemistry and hepatic antioxidant status of growing rabbits |
| topic | red hot pepper rabbits Mass detection antioxidants oxidative stress |
| url | https://www.mdpi.com/2076-2615/10/11/2045 |
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