Preoperative detection of gastrointestinal neuroendocrine tumors using endoscopic ultrasonography Detección preoperatoria de los tumores neuroendocrinos digestivos mediante ultrasonografía endoscópica
Objective: almost 30% of gastroenteropancreatic neuroendocrine tumors (GEPET) escape preoperative identification using standard imaging techniques. The goal of this retrospective study is to present our cumulative experience in the assessment of GEPET by preoperative endoscopic ultrasonography (EUS)...
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| Format: | Article |
| Language: | English |
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Aran Ediciones
2006-11-01
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| Series: | Revista Espanola de Enfermedades Digestivas |
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| Online Access: | http://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S1130-01082006001100004 |
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| author | M. J. Varas Lorenzo J. M. Miquel Collell M. D. Maluenda Colomer J. Boix Valverde J. R. Armengol Miró |
| author_facet | M. J. Varas Lorenzo J. M. Miquel Collell M. D. Maluenda Colomer J. Boix Valverde J. R. Armengol Miró |
| author_sort | M. J. Varas Lorenzo |
| collection | DOAJ |
| description | Objective: almost 30% of gastroenteropancreatic neuroendocrine tumors (GEPET) escape preoperative identification using standard imaging techniques. The goal of this retrospective study is to present our cumulative experience in the assessment of GEPET by preoperative endoscopic ultrasonography (EUS), and to compare it with a literature review. Patients and methods: thirty-seven patients with suspected specific hormonal syndromes were sequentially examined with US, CT, MRI, angiography, OctreoScan, and radial and sectorial EUS. Sixteen were males (43%) and 21 were females (57%), with a mean age of 61 years (interval: 40-84 a). Of all 37 patients, 27 had 19 endocrine tumors in the pancreas and 14 tumors in their gastrointestinal tract. No tumors were demonstrated in 10 patients, hence they were used as a control group. Of all 37 patients, 24 were operated on or had histological samples collected, with the presence of 26 GEPET (10 carcinoids) being confirmed in 22 patients. Results: EUS sensitivity and diagnostic accuracy were 81% and 78%. Specificity was 80%. All these values were similar to the mean values obtained from the literature review. Three pancreatic rumors smaller than or equal to 1 cm (insulinomas) were detected, which had escaped diagnosis with previous US, CT, and MRI studies. An echoendoscopic examination of the pancreas could not be completed in two cases (5%), a pancreas carcinoid and an already gastrectomized double pancreatic gastrinoma. Conclusion: EUS is a good preoperative technique for GEPET detection, and may likely be superior to other imaging techniques in the assessment of small tumors. The usefulness of EUS as a primary exploration after US or HCT has been posited for tumor diagnosis and localization before surgery. |
| first_indexed | 2024-12-24T04:17:02Z |
| format | Article |
| id | doaj.art-1c1c537a92854d34b138f8da43d06157 |
| institution | Directory Open Access Journal |
| issn | 1130-0108 |
| language | English |
| last_indexed | 2024-12-24T04:17:02Z |
| publishDate | 2006-11-01 |
| publisher | Aran Ediciones |
| record_format | Article |
| series | Revista Espanola de Enfermedades Digestivas |
| spelling | doaj.art-1c1c537a92854d34b138f8da43d061572022-12-21T17:15:54ZengAran EdicionesRevista Espanola de Enfermedades Digestivas1130-01082006-11-019811828836Preoperative detection of gastrointestinal neuroendocrine tumors using endoscopic ultrasonography Detección preoperatoria de los tumores neuroendocrinos digestivos mediante ultrasonografía endoscópicaM. J. Varas LorenzoJ. M. Miquel CollellM. D. Maluenda ColomerJ. Boix ValverdeJ. R. Armengol MiróObjective: almost 30% of gastroenteropancreatic neuroendocrine tumors (GEPET) escape preoperative identification using standard imaging techniques. The goal of this retrospective study is to present our cumulative experience in the assessment of GEPET by preoperative endoscopic ultrasonography (EUS), and to compare it with a literature review. Patients and methods: thirty-seven patients with suspected specific hormonal syndromes were sequentially examined with US, CT, MRI, angiography, OctreoScan, and radial and sectorial EUS. Sixteen were males (43%) and 21 were females (57%), with a mean age of 61 years (interval: 40-84 a). Of all 37 patients, 27 had 19 endocrine tumors in the pancreas and 14 tumors in their gastrointestinal tract. No tumors were demonstrated in 10 patients, hence they were used as a control group. Of all 37 patients, 24 were operated on or had histological samples collected, with the presence of 26 GEPET (10 carcinoids) being confirmed in 22 patients. Results: EUS sensitivity and diagnostic accuracy were 81% and 78%. Specificity was 80%. All these values were similar to the mean values obtained from the literature review. Three pancreatic rumors smaller than or equal to 1 cm (insulinomas) were detected, which had escaped diagnosis with previous US, CT, and MRI studies. An echoendoscopic examination of the pancreas could not be completed in two cases (5%), a pancreas carcinoid and an already gastrectomized double pancreatic gastrinoma. Conclusion: EUS is a good preoperative technique for GEPET detection, and may likely be superior to other imaging techniques in the assessment of small tumors. The usefulness of EUS as a primary exploration after US or HCT has been posited for tumor diagnosis and localization before surgery.http://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S1130-01082006001100004Neuroendocrine tumorsCarcinoid tumorsPancreatic endocrine tumorsEndoscopic ultrasonographyEndosonographyEchoendoscopy |
| spellingShingle | M. J. Varas Lorenzo J. M. Miquel Collell M. D. Maluenda Colomer J. Boix Valverde J. R. Armengol Miró Preoperative detection of gastrointestinal neuroendocrine tumors using endoscopic ultrasonography Detección preoperatoria de los tumores neuroendocrinos digestivos mediante ultrasonografía endoscópica Revista Espanola de Enfermedades Digestivas Neuroendocrine tumors Carcinoid tumors Pancreatic endocrine tumors Endoscopic ultrasonography Endosonography Echoendoscopy |
| title | Preoperative detection of gastrointestinal neuroendocrine tumors using endoscopic ultrasonography Detección preoperatoria de los tumores neuroendocrinos digestivos mediante ultrasonografía endoscópica |
| title_full | Preoperative detection of gastrointestinal neuroendocrine tumors using endoscopic ultrasonography Detección preoperatoria de los tumores neuroendocrinos digestivos mediante ultrasonografía endoscópica |
| title_fullStr | Preoperative detection of gastrointestinal neuroendocrine tumors using endoscopic ultrasonography Detección preoperatoria de los tumores neuroendocrinos digestivos mediante ultrasonografía endoscópica |
| title_full_unstemmed | Preoperative detection of gastrointestinal neuroendocrine tumors using endoscopic ultrasonography Detección preoperatoria de los tumores neuroendocrinos digestivos mediante ultrasonografía endoscópica |
| title_short | Preoperative detection of gastrointestinal neuroendocrine tumors using endoscopic ultrasonography Detección preoperatoria de los tumores neuroendocrinos digestivos mediante ultrasonografía endoscópica |
| title_sort | preoperative detection of gastrointestinal neuroendocrine tumors using endoscopic ultrasonography deteccion preoperatoria de los tumores neuroendocrinos digestivos mediante ultrasonografia endoscopica |
| topic | Neuroendocrine tumors Carcinoid tumors Pancreatic endocrine tumors Endoscopic ultrasonography Endosonography Echoendoscopy |
| url | http://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S1130-01082006001100004 |
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