Functional interplay between long non-coding RNAs and the Wnt signaling cascade in osteosarcoma

Functional interplay between long non-coding RNAs and the Wnt signaling cascade in osteosarcoma

Abstract Osteosarcoma is a common and highly malignant bone tumor among children, adolescents and young adults. However, the underlying molecular mechanisms remain largely unexplored. LncRNAs are transcripts with no or limited protein-coding capacity in human genomes, and have been demonstrated to p...

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Bibliographic Details
Main Authors: Jieyu He, Lin Ling, Zhongyue Liu, Xiaolei Ren, Lu Wan, Chao Tu, Zhihong Li
Format: Article
Language:English
Published: BMC 2021-06-01
Series:Cancer Cell International
Subjects:
LncRNA
Wnt
β-catenin
Osteosarcoma
Drug resistance
Stemness
Online Access:https://doi.org/10.1186/s12935-021-02013-8

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