OCT Findings in MINOCA

Myocardial infarction with non-obstructive coronary artery disease (MINOCA) is a working diagnosis for patients presenting with acute myocardial infarction without obstructive coronary artery disease on coronary angiography. It is a heterogenous entity with a number of possible etiologies that can b...

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Main Authors: Krzysztof Bryniarski, Pawel Gasior, Jacek Legutko, Dawid Makowicz, Anna Kedziora, Piotr Szolc, Leszek Bryniarski, Pawel Kleczynski, Ik-Kyung Jang
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Journal of Clinical Medicine
Subjects:
Online Access:https://www.mdpi.com/2077-0383/10/13/2759
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author Krzysztof Bryniarski
Pawel Gasior
Jacek Legutko
Dawid Makowicz
Anna Kedziora
Piotr Szolc
Leszek Bryniarski
Pawel Kleczynski
Ik-Kyung Jang
author_facet Krzysztof Bryniarski
Pawel Gasior
Jacek Legutko
Dawid Makowicz
Anna Kedziora
Piotr Szolc
Leszek Bryniarski
Pawel Kleczynski
Ik-Kyung Jang
author_sort Krzysztof Bryniarski
collection DOAJ
description Myocardial infarction with non-obstructive coronary artery disease (MINOCA) is a working diagnosis for patients presenting with acute myocardial infarction without obstructive coronary artery disease on coronary angiography. It is a heterogenous entity with a number of possible etiologies that can be determined through the use of appropriate diagnostic algorithms. Common causes of a MINOCA may include plaque disruption, spontaneous coronary artery dissection, coronary artery spasm, and coronary thromboembolism. Optical coherence tomography (OCT) is an intravascular imaging modality which allows the differentiation of coronary tissue morphological characteristics including the identification of thin cap fibroatheroma and the differentiation between plaque rupture or erosion, due to its high resolution. In this narrative review we will discuss the role of OCT in patients presenting with MINOCA. In this group of patients OCT has been shown to reveal abnormal findings in almost half of the cases. Moreover, combining OCT with cardiac magnetic resonance (CMR) was shown to allow the identification of most of the underlying mechanisms of MINOCA. Hence, it is recommended that both OCT and CMR can be used in patients with a working diagnosis of MINOCA. Well-designed prospective studies are needed in order to gain a better understanding of this condition and to provide optimal management while reducing morbidity and mortality in that subset patients.
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spelling doaj.art-1c1ef7e0f04d40378ed6d20cfb6e28dd2023-11-22T01:24:38ZengMDPI AGJournal of Clinical Medicine2077-03832021-06-011013275910.3390/jcm10132759OCT Findings in MINOCAKrzysztof Bryniarski0Pawel Gasior1Jacek Legutko2Dawid Makowicz3Anna Kedziora4Piotr Szolc5Leszek Bryniarski6Pawel Kleczynski7Ik-Kyung Jang8Jagiellonian University Medical College, Institute of Cardiology, Department of Interventional Cardiology, John Paul II Hospital, 31-202 Krakow, PolandDivision of Cardiology and Structural Heart Diseases, Medical University of Silesia, 40-635 Katowice, PolandJagiellonian University Medical College, Institute of Cardiology, Department of Interventional Cardiology, John Paul II Hospital, 31-202 Krakow, PolandInterventional Cardiology, Electrotherapy and Angiology Department, John Paul II Hospital, 38-400 Krosno, PolandDepartment of Cardiovascular Surgery and Transplantation, John Paul II Hospital, 31-202 Krakow, PolandJagiellonian University Medical College, Institute of Cardiology, Department of Interventional Cardiology, John Paul II Hospital, 31-202 Krakow, Poland2nd Department of Cardiology and Cardiovascular Interventions, University Hospital, Institute of Cardiology, Jagiellonian University Medical College, 31-501 Krakow, PolandJagiellonian University Medical College, Institute of Cardiology, Department of Interventional Cardiology, John Paul II Hospital, 31-202 Krakow, PolandCardiology Division, Massachusetts General Hospital, Harvard Medical School, 55 Fruit Street|GRB 800, Boston, MA 02114, USAMyocardial infarction with non-obstructive coronary artery disease (MINOCA) is a working diagnosis for patients presenting with acute myocardial infarction without obstructive coronary artery disease on coronary angiography. It is a heterogenous entity with a number of possible etiologies that can be determined through the use of appropriate diagnostic algorithms. Common causes of a MINOCA may include plaque disruption, spontaneous coronary artery dissection, coronary artery spasm, and coronary thromboembolism. Optical coherence tomography (OCT) is an intravascular imaging modality which allows the differentiation of coronary tissue morphological characteristics including the identification of thin cap fibroatheroma and the differentiation between plaque rupture or erosion, due to its high resolution. In this narrative review we will discuss the role of OCT in patients presenting with MINOCA. In this group of patients OCT has been shown to reveal abnormal findings in almost half of the cases. Moreover, combining OCT with cardiac magnetic resonance (CMR) was shown to allow the identification of most of the underlying mechanisms of MINOCA. Hence, it is recommended that both OCT and CMR can be used in patients with a working diagnosis of MINOCA. Well-designed prospective studies are needed in order to gain a better understanding of this condition and to provide optimal management while reducing morbidity and mortality in that subset patients.https://www.mdpi.com/2077-0383/10/13/2759cardiovascular diseaseacute myocardial infarctionintravascular imaging
spellingShingle Krzysztof Bryniarski
Pawel Gasior
Jacek Legutko
Dawid Makowicz
Anna Kedziora
Piotr Szolc
Leszek Bryniarski
Pawel Kleczynski
Ik-Kyung Jang
OCT Findings in MINOCA
Journal of Clinical Medicine
cardiovascular disease
acute myocardial infarction
intravascular imaging
title OCT Findings in MINOCA
title_full OCT Findings in MINOCA
title_fullStr OCT Findings in MINOCA
title_full_unstemmed OCT Findings in MINOCA
title_short OCT Findings in MINOCA
title_sort oct findings in minoca
topic cardiovascular disease
acute myocardial infarction
intravascular imaging
url https://www.mdpi.com/2077-0383/10/13/2759
work_keys_str_mv AT krzysztofbryniarski octfindingsinminoca
AT pawelgasior octfindingsinminoca
AT jaceklegutko octfindingsinminoca
AT dawidmakowicz octfindingsinminoca
AT annakedziora octfindingsinminoca
AT piotrszolc octfindingsinminoca
AT leszekbryniarski octfindingsinminoca
AT pawelkleczynski octfindingsinminoca
AT ikkyungjang octfindingsinminoca