OCT Findings in MINOCA
Myocardial infarction with non-obstructive coronary artery disease (MINOCA) is a working diagnosis for patients presenting with acute myocardial infarction without obstructive coronary artery disease on coronary angiography. It is a heterogenous entity with a number of possible etiologies that can b...
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MDPI AG
2021-06-01
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author | Krzysztof Bryniarski Pawel Gasior Jacek Legutko Dawid Makowicz Anna Kedziora Piotr Szolc Leszek Bryniarski Pawel Kleczynski Ik-Kyung Jang |
author_facet | Krzysztof Bryniarski Pawel Gasior Jacek Legutko Dawid Makowicz Anna Kedziora Piotr Szolc Leszek Bryniarski Pawel Kleczynski Ik-Kyung Jang |
author_sort | Krzysztof Bryniarski |
collection | DOAJ |
description | Myocardial infarction with non-obstructive coronary artery disease (MINOCA) is a working diagnosis for patients presenting with acute myocardial infarction without obstructive coronary artery disease on coronary angiography. It is a heterogenous entity with a number of possible etiologies that can be determined through the use of appropriate diagnostic algorithms. Common causes of a MINOCA may include plaque disruption, spontaneous coronary artery dissection, coronary artery spasm, and coronary thromboembolism. Optical coherence tomography (OCT) is an intravascular imaging modality which allows the differentiation of coronary tissue morphological characteristics including the identification of thin cap fibroatheroma and the differentiation between plaque rupture or erosion, due to its high resolution. In this narrative review we will discuss the role of OCT in patients presenting with MINOCA. In this group of patients OCT has been shown to reveal abnormal findings in almost half of the cases. Moreover, combining OCT with cardiac magnetic resonance (CMR) was shown to allow the identification of most of the underlying mechanisms of MINOCA. Hence, it is recommended that both OCT and CMR can be used in patients with a working diagnosis of MINOCA. Well-designed prospective studies are needed in order to gain a better understanding of this condition and to provide optimal management while reducing morbidity and mortality in that subset patients. |
first_indexed | 2024-03-10T10:07:14Z |
format | Article |
id | doaj.art-1c1ef7e0f04d40378ed6d20cfb6e28dd |
institution | Directory Open Access Journal |
issn | 2077-0383 |
language | English |
last_indexed | 2024-03-10T10:07:14Z |
publishDate | 2021-06-01 |
publisher | MDPI AG |
record_format | Article |
series | Journal of Clinical Medicine |
spelling | doaj.art-1c1ef7e0f04d40378ed6d20cfb6e28dd2023-11-22T01:24:38ZengMDPI AGJournal of Clinical Medicine2077-03832021-06-011013275910.3390/jcm10132759OCT Findings in MINOCAKrzysztof Bryniarski0Pawel Gasior1Jacek Legutko2Dawid Makowicz3Anna Kedziora4Piotr Szolc5Leszek Bryniarski6Pawel Kleczynski7Ik-Kyung Jang8Jagiellonian University Medical College, Institute of Cardiology, Department of Interventional Cardiology, John Paul II Hospital, 31-202 Krakow, PolandDivision of Cardiology and Structural Heart Diseases, Medical University of Silesia, 40-635 Katowice, PolandJagiellonian University Medical College, Institute of Cardiology, Department of Interventional Cardiology, John Paul II Hospital, 31-202 Krakow, PolandInterventional Cardiology, Electrotherapy and Angiology Department, John Paul II Hospital, 38-400 Krosno, PolandDepartment of Cardiovascular Surgery and Transplantation, John Paul II Hospital, 31-202 Krakow, PolandJagiellonian University Medical College, Institute of Cardiology, Department of Interventional Cardiology, John Paul II Hospital, 31-202 Krakow, Poland2nd Department of Cardiology and Cardiovascular Interventions, University Hospital, Institute of Cardiology, Jagiellonian University Medical College, 31-501 Krakow, PolandJagiellonian University Medical College, Institute of Cardiology, Department of Interventional Cardiology, John Paul II Hospital, 31-202 Krakow, PolandCardiology Division, Massachusetts General Hospital, Harvard Medical School, 55 Fruit Street|GRB 800, Boston, MA 02114, USAMyocardial infarction with non-obstructive coronary artery disease (MINOCA) is a working diagnosis for patients presenting with acute myocardial infarction without obstructive coronary artery disease on coronary angiography. It is a heterogenous entity with a number of possible etiologies that can be determined through the use of appropriate diagnostic algorithms. Common causes of a MINOCA may include plaque disruption, spontaneous coronary artery dissection, coronary artery spasm, and coronary thromboembolism. Optical coherence tomography (OCT) is an intravascular imaging modality which allows the differentiation of coronary tissue morphological characteristics including the identification of thin cap fibroatheroma and the differentiation between plaque rupture or erosion, due to its high resolution. In this narrative review we will discuss the role of OCT in patients presenting with MINOCA. In this group of patients OCT has been shown to reveal abnormal findings in almost half of the cases. Moreover, combining OCT with cardiac magnetic resonance (CMR) was shown to allow the identification of most of the underlying mechanisms of MINOCA. Hence, it is recommended that both OCT and CMR can be used in patients with a working diagnosis of MINOCA. Well-designed prospective studies are needed in order to gain a better understanding of this condition and to provide optimal management while reducing morbidity and mortality in that subset patients.https://www.mdpi.com/2077-0383/10/13/2759cardiovascular diseaseacute myocardial infarctionintravascular imaging |
spellingShingle | Krzysztof Bryniarski Pawel Gasior Jacek Legutko Dawid Makowicz Anna Kedziora Piotr Szolc Leszek Bryniarski Pawel Kleczynski Ik-Kyung Jang OCT Findings in MINOCA Journal of Clinical Medicine cardiovascular disease acute myocardial infarction intravascular imaging |
title | OCT Findings in MINOCA |
title_full | OCT Findings in MINOCA |
title_fullStr | OCT Findings in MINOCA |
title_full_unstemmed | OCT Findings in MINOCA |
title_short | OCT Findings in MINOCA |
title_sort | oct findings in minoca |
topic | cardiovascular disease acute myocardial infarction intravascular imaging |
url | https://www.mdpi.com/2077-0383/10/13/2759 |
work_keys_str_mv | AT krzysztofbryniarski octfindingsinminoca AT pawelgasior octfindingsinminoca AT jaceklegutko octfindingsinminoca AT dawidmakowicz octfindingsinminoca AT annakedziora octfindingsinminoca AT piotrszolc octfindingsinminoca AT leszekbryniarski octfindingsinminoca AT pawelkleczynski octfindingsinminoca AT ikkyungjang octfindingsinminoca |