The roles of P2Y2 purinergic receptors in osteoblasts and mechanotransduction.

The roles of P2Y2 purinergic receptors in osteoblasts and mechanotransduction.

We previously demonstrated, using osteoblastic MC3T3-E1 cells, that P2Y2 purinergic receptors are involved in osteoblast mechanotransduction. In this study, our objective was to further investigate, using a knockout mouse model, the roles of P2Y2 receptors in bone mechanobiology. We first examined b...

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Bibliographic Details
Main Authors: Yanghui Xing, Yan Gu, James J Bresnahan, Emmanuel M Paul, Henry J Donahue, Jun You
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4182465?pdf=render

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