Development of a Solid Dispersion of Nystatin with Maltodextrin as a Carrier Agent: Improvements in Antifungal Efficacy against <i>Candida</i> spp. Biofilm Infections

Development of a Solid Dispersion of Nystatin with Maltodextrin as a Carrier Agent: Improvements in Antifungal Efficacy against <i>Candida</i> spp. Biofilm Infections

The aim of this study was to improve the treatment of <i>Candida albicans</i> biofilms through the use of nystatin solid dispersions developed using maltodextrins as a hyperosmotic carrier. Characterization studies by differential scanning calorimetry, X-ray diffraction, dissolution stud...

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Bibliographic Details
Main Authors: Carlos Benavent, Carlos Torrado-Salmerón, Santiago Torrado-Santiago
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Pharmaceuticals
Subjects:
solid dispersion
nystatin
amorphous form
maltodextrin
biofilms
<i>Candida albicans</i>
Online Access:https://www.mdpi.com/1424-8247/14/5/397

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