Clinical features, Cardiac magnetic resonance imaging findings and outcome of patients with suspected myocarditis

Myocarditis is largely underdiagnosed due to subclinical symptoms and non-availability of diagnostic techniques necessitating high index of suspicion and early disease identification. This study aimed to assess the clinical presentation, cardiac magnetic resonance (CMR) imaging findings and prognos...

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Main Authors: Salik Ur Rehman Iqbal, Fateh Ali Tipoo Sultan
Format: Article
Language:English
Published: Pakistan Medical Association 2021-07-01
Series:Journal of the Pakistan Medical Association
Online Access:https://www.ojs.jpma.org.pk/index.php/public_html/article/view/277
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author Salik Ur Rehman Iqbal
Fateh Ali Tipoo Sultan
author_facet Salik Ur Rehman Iqbal
Fateh Ali Tipoo Sultan
author_sort Salik Ur Rehman Iqbal
collection DOAJ
description Myocarditis is largely underdiagnosed due to subclinical symptoms and non-availability of diagnostic techniques necessitating high index of suspicion and early disease identification. This study aimed to assess the clinical presentation, cardiac magnetic resonance (CMR) imaging findings and prognosis of these patients. After reviewing the CMR data of Aga Khan University Hospital from January 2011 to December 2019, a total of 24 patients were included with the confirmed diagnosis of myocarditis on CMR. Mean age was 33.4 +15 years with the majority (58%) being male. Dyspnea (n = 15, 62%) was the commonest symptom followed by chest pain (n = 13, 54%). On echocardiogram, 55% showed LV dysfunction. Common CMR findings were late gadolinium enhancement (n=18, 75%) and bright T2 signals (n=11, 45%).  With a mean follow-up of 3.6 + 2.0 years, one patient died of non-cardiac cause. More than half (60%) had resolution of LV dysfunction suggesting favorable prognosis. Continuous...
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spelling doaj.art-1c2999f35faa4d0ca224f6f3720eeaa62023-05-25T04:24:25ZengPakistan Medical AssociationJournal of the Pakistan Medical Association0030-99822021-07-01711010.47391/JPMA.02-277Clinical features, Cardiac magnetic resonance imaging findings and outcome of patients with suspected myocarditisSalik Ur Rehman Iqbal0Fateh Ali Tipoo Sultan1Department of Medicine, Aga Khan University Hospital, Karachi, PakistanDepartment of Medicine, Aga Khan University Hospital, Karachi, Pakistan Myocarditis is largely underdiagnosed due to subclinical symptoms and non-availability of diagnostic techniques necessitating high index of suspicion and early disease identification. This study aimed to assess the clinical presentation, cardiac magnetic resonance (CMR) imaging findings and prognosis of these patients. After reviewing the CMR data of Aga Khan University Hospital from January 2011 to December 2019, a total of 24 patients were included with the confirmed diagnosis of myocarditis on CMR. Mean age was 33.4 +15 years with the majority (58%) being male. Dyspnea (n = 15, 62%) was the commonest symptom followed by chest pain (n = 13, 54%). On echocardiogram, 55% showed LV dysfunction. Common CMR findings were late gadolinium enhancement (n=18, 75%) and bright T2 signals (n=11, 45%).  With a mean follow-up of 3.6 + 2.0 years, one patient died of non-cardiac cause. More than half (60%) had resolution of LV dysfunction suggesting favorable prognosis. Continuous... https://www.ojs.jpma.org.pk/index.php/public_html/article/view/277
spellingShingle Salik Ur Rehman Iqbal
Fateh Ali Tipoo Sultan
Clinical features, Cardiac magnetic resonance imaging findings and outcome of patients with suspected myocarditis
Journal of the Pakistan Medical Association
title Clinical features, Cardiac magnetic resonance imaging findings and outcome of patients with suspected myocarditis
title_full Clinical features, Cardiac magnetic resonance imaging findings and outcome of patients with suspected myocarditis
title_fullStr Clinical features, Cardiac magnetic resonance imaging findings and outcome of patients with suspected myocarditis
title_full_unstemmed Clinical features, Cardiac magnetic resonance imaging findings and outcome of patients with suspected myocarditis
title_short Clinical features, Cardiac magnetic resonance imaging findings and outcome of patients with suspected myocarditis
title_sort clinical features cardiac magnetic resonance imaging findings and outcome of patients with suspected myocarditis
url https://www.ojs.jpma.org.pk/index.php/public_html/article/view/277
work_keys_str_mv AT salikurrehmaniqbal clinicalfeaturescardiacmagneticresonanceimagingfindingsandoutcomeofpatientswithsuspectedmyocarditis
AT fatehalitipoosultan clinicalfeaturescardiacmagneticresonanceimagingfindingsandoutcomeofpatientswithsuspectedmyocarditis