Inhibition effect of B7-H1 gene-modified regulatory dendritic cells on thyroid-associated ophthalmopathy in mice

Inhibition effect of B7-H1 gene-modified regulatory dendritic cells on thyroid-associated ophthalmopathy in mice

AIM:To construct adenovirus vector expressing mice B7-H1 gene, transfect dendritic cells(DCs), and to study the therapeutic effect of modified DC on thyroid-associated ophthalmopathy(TAO)in mice.<p>METHODS: We designed and constructed B7-H1 gene adenovirus expression vector, and transfected DC...

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Bibliographic Details
Main Authors: Hua-Xin Chen, Bo-Zong Shao, Xuan-Chen Chen, Wei-Ming Zhou, Yi Zhang
Format: Article
Language:English
Published: Press of International Journal of Ophthalmology (IJO PRESS) 2014-10-01
Series:Guoji Yanke Zazhi
Subjects:
B7-H1
dendritic cells
adenovirus vector
thyroid-associated ophthalmopathy
negative immun- oregulation
Online Access:http://www.ies.net.cn/cn_publish/2014/10/201410006.pdf

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