Altered hepatic lipid droplet morphology and lipid metabolism in fasted Plin2-null mice

Altered hepatic lipid droplet morphology and lipid metabolism in fasted Plin2-null mice

Perilipin 2 (Plin2) binds to the surface of hepatic lipid droplets (LDs) with expression levels that correlate with triacylglyceride (TAG) content. We investigated if Plin2 is important for hepatic LD storage in fasted or high-fat diet-induced obese Plin2+/+ and Plin2−/− mice. Plin2−/− mice had comp...

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Bibliographic Details
Main Authors: Atanaska I. Doncheva, Yuchuan Li, Prabhat Khanal, Marit Hjorth, Svein O. Kolset, Frode A. Norheim, Alan R. Kimmel, Knut Tomas Dalen
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:Journal of Lipid Research
Subjects:
Plin2
liver
triglyceride
cholesteryl ester
lipid droplets
fasting
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227523001347

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