Synthetic and immunological studies on the OCT4 immunodominant motif antigen-based anti-cancer vaccine

Synthetic and immunological studies on the OCT4 immunodominant motif antigen-based anti-cancer vaccine

Objective: Cancer stem cell is one of the important causes of tumorigenesis as well as a drug target in the treatment of malignant tumor. However, at present, there is no immune vaccine targeting these cells. Octamer-binding transcription factor 4 (OCT4), a marker of embryonic stem cells and germ ce...

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Bibliographic Details
Main Authors: Tingting Chen, Kan Liu, Jiangyao Xu, Tianying Zhan, Maixian Liu, Li Li, Zhiwen Yang, Shuping Yuan, Wenyi Zou, Guimiao Lin, Dennis A. Carson, Christina C. N. Wu, Xiaomei Wang
Format: Article
Language:English
Published: China Anti-Cancer Association 2020-02-01
Series:Cancer Biology & Medicine
Subjects:
cancer prevention
cancer immunology
oct4
tlr9 agonist
Online Access:http://www.cancerbiomed.org/index.php/cocr/article/view/1571

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