Histological Type, Cytotoxic T Cells and Macrophages in the Tumor Microenvironment Affect the PD-L1 Status of Gastric Cancer

Histological Type, Cytotoxic T Cells and Macrophages in the Tumor Microenvironment Affect the PD-L1 Status of Gastric Cancer

Gastric cancer (GC) therapies include gastrectomy and chemoradiotherapy. The tumor immune microenvironment (TME) has implications for potential immunotherapy. We analyzed the expression of PD-L1, CD8, CTLA-4 and IFN-γ in the tumor and regional lymph node (LN) of patients with GC and compared it with...

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Bibliographic Details
Main Authors: Tomislav Ivanović, Dorotea Božić, Benjamin Benzon, Vesna Čapkun, Katarina Vukojević, Merica Glavina Durdov
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Biomedicines
Subjects:
gastric cancer
tumor immune microenvironment
PD-L1
CTLA-4
IFN-γ
Online Access:https://www.mdpi.com/2227-9059/11/3/709

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