Blood-nerve barrier disruption and coagulation system activation induced by mechanical compression injury participate in the peripheral sensitization of trigeminal neuralgia

Blood-nerve barrier disruption and coagulation system activation induced by mechanical compression injury participate in the peripheral sensitization of trigeminal neuralgia

IntroductionThe aim of this study was to investigate the effect and possible mechanisms of the blood-nerve barrier (BNB) and the coagulation-anticoagulation system in modulating the mechanical allodynia in a trigeminal neuralgia (TN) rat model induced by chronic compression of the trigeminal root en...

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Bibliographic Details
Main Authors:	Lu-Xi Zhou, Shao-Wei Lin, Rong-Hui Qiu, Ling Lin, Yue-Feng Guo, Dao-Shu Luo, Yun-Qing Li, Feng Wang
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2022-12-01
Series:	Frontiers in Molecular Neuroscience
Subjects:	mechanical compression trigeminal root entry zone blood-nerve barrier nodes of Ranvier neurofascin-155 protease-activated receptor 1
Online Access:	https://www.frontiersin.org/articles/10.3389/fnmol.2022.1059980/full

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