Suppression of cell migration by phospholipase C-related catalytically inactive protein-dependent modulation of PI3K signalling

Suppression of cell migration by phospholipase C-related catalytically inactive protein-dependent modulation of PI3K signalling

Abstract The metabolic processes of phosphatidylinositol 4,5-bisphosphate [PI(4,5)P2] into PI(3,4,5)P3 and the subsequent PI(3,4,5)P3 signalling are involved in cell migration. Dysfunctions in the control of this pathway can cause human cancer cell migration and metastatic growth. Here we investigat...

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Bibliographic Details
Main Authors: Satoshi Asano, Yuri Taniguchi, Yosuke Yamawaki, Jing Gao, Kae Harada, Hiroshi Takeuchi, Masato Hirata, Takashi Kanematsu
Format: Article
Language:English
Published: Nature Portfolio 2017-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-05908-7

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