Effects of Real-Ambient PM2.5 Exposure on Lung Damage Modulated by Nrf2−/−

Effects of Real-Ambient PM2.5 Exposure on Lung Damage Modulated by Nrf2−/−

Previous studies have shown that long-term exposure to fine particulate matter (PM2.5) increases the morbidity and mortality of pulmonary diseases such as asthma, chronic obstructive pulmonary disease and pulmonary emphysema. Oxidative stress and inflammation play key roles in pulmonary damage cause...

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Bibliographic Details
Main Authors: Hao Ding, Menghui Jiang, Daochuan Li, Yanjie Zhao, Dianke Yu, Rong Zhang, Wen Chen, Jingbo Pi, Rui Chen, Lianhua Cui, Yuxin Zheng, Jinmei Piao
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Pharmacology
Subjects:
Nrf2
CYP450
lung
PM2.5
endoplasmic reticulum stress
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.662664/full

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