Different Pathways Conferring Integrase Strand-Transfer Inhibitors Resistance

Different Pathways Conferring Integrase Strand-Transfer Inhibitors Resistance

Integrase Strand Transfer Inhibitors (INSTIs) are currently used as the most effective therapy in the treatment of human immunodeficiency virus (HIV) infections. Raltegravir (RAL) and Elvitegravir (EVG), the first generation of INSTIs used successfully in clinical treatment, are susceptible to the e...

Full description

Bibliographic Details
Main Authors: Clémence Richetta, Nhat Quang Tu, Olivier Delelis
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Viruses
Subjects:
HIV-1
strand-transfer inhibitors
integrase
unintegrated viral DNA
resistance
Online Access:https://www.mdpi.com/1999-4915/14/12/2591

Similar Items

Similar Items