Coherent Raman scattering imaging with a near-infrared achromatic metalens

Miniature handheld imaging devices and endoscopes based on coherent Raman scattering are promising for label-free in vivo optical diagnosis. Toward the development of these small-scale systems, a challenge arises from the design and fabrication of achromatic and high-end miniature optical components...

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Main Authors: Peng Lin, Wei Ting Chen, Kerolos M. A. Yousef, Justin Marchioni, Alexander Zhu, Federico Capasso, Ji-Xin Cheng
Format: Article
Language:English
Published: AIP Publishing LLC 2021-09-01
Series:APL Photonics
Online Access:http://dx.doi.org/10.1063/5.0059874
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author Peng Lin
Wei Ting Chen
Kerolos M. A. Yousef
Justin Marchioni
Alexander Zhu
Federico Capasso
Ji-Xin Cheng
author_facet Peng Lin
Wei Ting Chen
Kerolos M. A. Yousef
Justin Marchioni
Alexander Zhu
Federico Capasso
Ji-Xin Cheng
author_sort Peng Lin
collection DOAJ
description Miniature handheld imaging devices and endoscopes based on coherent Raman scattering are promising for label-free in vivo optical diagnosis. Toward the development of these small-scale systems, a challenge arises from the design and fabrication of achromatic and high-end miniature optical components for both pump and Stokes laser wavelengths. Here, we report a metasurface converting a low-cost plano–convex lens into a water-immersion, nearly diffraction-limited and achromatic lens. The metasurface comprising amorphous silicon nanopillars is designed in a way that all incident rays arrive at the focus with the same phase and group delay, leading to corrections of monochromatic and chromatic aberrations of the refractive lens, respectively. Compared to the case without the metasurface, the hybrid metasurface-refractive lens has higher Strehl ratios than the plano–convex lens and a tighter depth of focus. The hybrid metasurface-refractive lens is utilized in spectroscopic stimulated Raman scattering and coherent anti-Stokes Raman scattering imaging for the differentiation of two different polymer microbeads. Subsequently, the hybrid metalens is harnessed for volumetric coherent Raman scattering imaging of bead and tissue samples. Finally, we discuss possible approaches to integrate such hybrid metalens in a miniature scanning system for label-free coherent Raman scattering endoscopes.
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spelling doaj.art-1c433611af8543dda9e9accd49b9ea532022-12-21T23:11:33ZengAIP Publishing LLCAPL Photonics2378-09672021-09-0169096107096107-1010.1063/5.0059874Coherent Raman scattering imaging with a near-infrared achromatic metalensPeng Lin0Wei Ting Chen1Kerolos M. A. Yousef2Justin Marchioni3Alexander Zhu4Federico Capasso5Ji-Xin Cheng6Department of Electrical and Computer Engineering, Boston University, Boston, Massachusetts 02215, USAJohn A. Paulson School of Engineering and Applied Sciences, Harvard University, Cambridge, Massachusetts 02138, USAJohn A. Paulson School of Engineering and Applied Sciences, Harvard University, Cambridge, Massachusetts 02138, USAJohn A. Paulson School of Engineering and Applied Sciences, Harvard University, Cambridge, Massachusetts 02138, USAJohn A. Paulson School of Engineering and Applied Sciences, Harvard University, Cambridge, Massachusetts 02138, USAJohn A. Paulson School of Engineering and Applied Sciences, Harvard University, Cambridge, Massachusetts 02138, USADepartment of Electrical and Computer Engineering, Boston University, Boston, Massachusetts 02215, USAMiniature handheld imaging devices and endoscopes based on coherent Raman scattering are promising for label-free in vivo optical diagnosis. Toward the development of these small-scale systems, a challenge arises from the design and fabrication of achromatic and high-end miniature optical components for both pump and Stokes laser wavelengths. Here, we report a metasurface converting a low-cost plano–convex lens into a water-immersion, nearly diffraction-limited and achromatic lens. The metasurface comprising amorphous silicon nanopillars is designed in a way that all incident rays arrive at the focus with the same phase and group delay, leading to corrections of monochromatic and chromatic aberrations of the refractive lens, respectively. Compared to the case without the metasurface, the hybrid metasurface-refractive lens has higher Strehl ratios than the plano–convex lens and a tighter depth of focus. The hybrid metasurface-refractive lens is utilized in spectroscopic stimulated Raman scattering and coherent anti-Stokes Raman scattering imaging for the differentiation of two different polymer microbeads. Subsequently, the hybrid metalens is harnessed for volumetric coherent Raman scattering imaging of bead and tissue samples. Finally, we discuss possible approaches to integrate such hybrid metalens in a miniature scanning system for label-free coherent Raman scattering endoscopes.http://dx.doi.org/10.1063/5.0059874
spellingShingle Peng Lin
Wei Ting Chen
Kerolos M. A. Yousef
Justin Marchioni
Alexander Zhu
Federico Capasso
Ji-Xin Cheng
Coherent Raman scattering imaging with a near-infrared achromatic metalens
APL Photonics
title Coherent Raman scattering imaging with a near-infrared achromatic metalens
title_full Coherent Raman scattering imaging with a near-infrared achromatic metalens
title_fullStr Coherent Raman scattering imaging with a near-infrared achromatic metalens
title_full_unstemmed Coherent Raman scattering imaging with a near-infrared achromatic metalens
title_short Coherent Raman scattering imaging with a near-infrared achromatic metalens
title_sort coherent raman scattering imaging with a near infrared achromatic metalens
url http://dx.doi.org/10.1063/5.0059874
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