Seco-Tetracenomycins from the Marine-Derived Actinomycete Saccharothrix sp. 10-10

Seco-Tetracenomycins from the Marine-Derived Actinomycete Saccharothrix sp. 10-10

Six new tetracenomycin congeners, saccharothrixones E–I (1–5) and 13-de-O-methyltetracenomycin X (6), were isolated from the rare marine-derived actinomycete Saccharothrix sp. 10-10. Their structures were elucidated by spectroscopic analysis and time-dependent density functional...

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Bibliographic Details
Main Authors: Bin Liu, Jiao Li, Minghua Chen, Xiaomeng Hao, Fei Cao, Yi Tan, Yuhui Ping, Yiguang Wang, Chunling Xiao, Maoluo Gan
Format: Article
Language:English
Published: MDPI AG 2018-09-01
Series:Marine Drugs
Subjects:
marine actinomycete
Saccharothrix sp.
seco-tetracenomycin
saccharothrixone
structure-activity relationship
Online Access:http://www.mdpi.com/1660-3397/16/10/345

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