Inhibition of the SOCS1-JAK2-STAT3 Signaling Pathway Confers Neuroprotection in Rats with Ischemic Stroke

Inhibition of the SOCS1-JAK2-STAT3 Signaling Pathway Confers Neuroprotection in Rats with Ischemic Stroke

Background: The present study aims to investigate the protective effects of the SOCS1-JAK2-STAT3 signaling pathway on neurons in a rat model of ischemic stroke. Methods: Our study was conducted using an ischemic stroke rat model. After the microglia were extracted, 40 neonatal Sprague-Dawley (SD) ra...

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Bibliographic Details
Main Authors: Xiao-Lei Wang, Chun-Mei Qiao, Jiong-Ou Liu, Chun-Yang Li
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2017-11-01
Series:Cellular Physiology and Biochemistry
Subjects:
Ischemic stroke
SOCS1
JAK2
STAT3
Signaling pathway
Neuron
Online Access:https://www.karger.com/Article/FullText/484585

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