The effect of spironolactone on calcineurin inhibitor induced nephrotoxicity: a multicenter randomized, double-blind, clinical trial (the SPIREN trial)
Abstract Background Calcineurin inhibitor induced nephrotoxicity contributes to late allograft failure in kidney transplant patients. Evidence points towards aldosterone to play a role in the development of fibrosis in multiple organs. Animal studies have indicated a beneficial effect of mineralocor...
| Main Authors: | , , , , , |
|---|---|
| 格式: | Article |
| 語言: | English |
| 出版: |
BMC
2018-05-01
|
| 叢編: | BMC Nephrology |
| 主題: | |
| 在線閱讀: | http://link.springer.com/article/10.1186/s12882-018-0885-6 |