The stem cell–specific long noncoding RNA HOXA10-AS in the pathogenesis of KMT2A-rearranged leukemia

Abstract: HOX genes are highly conserved, and their precisely controlled expression is crucial for normal hematopoiesis. Accordingly, deregulation of HOX genes can cause leukemia. However, despite of intensive research on the coding HOX genes, the role of the numerous long noncoding RNAs (lncRNAs) w...

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Detalles Bibliográficos
Autores principales: Sina Al-Kershi, Raj Bhayadia, Michelle Ng, Lonneke Verboon, Stephan Emmrich, Lucie Gack, Adrian Schwarzer, Till Strowig, Dirk Heckl, Jan-Henning Klusmann
Formato: Artículo
Lenguaje:English
Publicado: Elsevier 2019-12-01
Colección:Blood Advances
Acceso en línea:http://www.sciencedirect.com/science/article/pii/S2473952920317146