Overexpression of PTPRN Promotes Metastasis of Lung Adenocarcinoma and Suppresses NK Cell Cytotoxicity

Overexpression of PTPRN Promotes Metastasis of Lung Adenocarcinoma and Suppresses NK Cell Cytotoxicity

BackgroundLung adenocarcinoma (LUAD) is the most common diagnostic histologic subtype of non-small cell lung cancer, but the role of receptor-type tyrosine-protein phosphatase-like N (PTPRN) in LUAD has not been studied.MethodsWe conducted a bioinformatic analysis to identify the expression of PTPRN...

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Bibliographic Details
Main Authors: Xinyue Song, Xue Jiao, Han Yan, Lifeng Yu, Longyang Jiang, Ming Zhang, Lianze Chen, Mingyi Ju, Lin Wang, Qian Wei, Lin Zhao, Minjie Wei
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
PTPRN
LUAD
EMT
tumor-infiltrating immune cells
NK cells
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.622018/full

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