Drug repositioning based on individual bi-random walks on a heterogeneous network

Drug repositioning based on individual bi-random walks on a heterogeneous network

Abstract Background Traditional drug research and development is high cost, time-consuming and risky. Computationally identifying new indications for existing drugs, referred as drug repositioning, greatly reduces the cost and attracts ever-increasing research interests. Many network-based methods h...

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Bibliographic Details
Main Authors: Yuehui Wang, Maozu Guo, Yazhou Ren, Lianyin Jia, Guoxian Yu
Format: Article
Language:English
Published: BMC 2019-12-01
Series:BMC Bioinformatics
Subjects:
Drug repositioning
Drug-disease heterogeneous network
Individual walk-length
Bi-random walks
Online Access:https://doi.org/10.1186/s12859-019-3117-6

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