Pharmacological Inhibition of S-Nitrosoglutathione Reductase Reduces Cardiac Damage Induced by Ischemia–Reperfusion

Pharmacological Inhibition of S-Nitrosoglutathione Reductase Reduces Cardiac Damage Induced by Ischemia–Reperfusion

The cardioprotective effects of nitric oxide (NO) have been described through S-nitrosylation of several important proteins in the mitochondria of the cardiomyocyte. S-nitrosoglutathione reductase (GSNOR) is an enzyme involved in the metabolism of S-nitrosothiols by producing denitrosylation, thus l...

ver descrição completa

Detalhes bibliográficos
Main Authors:	Oscar Arriagada Castillo, Gustavo Herrera, Carlos Manriquez, Andrea F. Rojas, Daniel R. González
Formato:	Artigo
Idioma:	English
Publicado em:	MDPI AG 2021-04-01
Colecção:	Antioxidants
Assuntos:	S-nitrosylation heart GSNOR mitochondria
Acesso em linha:	https://www.mdpi.com/2076-3921/10/4/555

Registos relacionados

S-nitrosoglutathione reductase alleviates morphine analgesic tolerance by restricting PKCα S-nitrosation
Por: Ling-Yan Su, et al.
Publicado em: (2024-09-01)

The Physiological Implications of <i>S</i>-Nitrosoglutathione Reductase (GSNOR) Activity Mediating NO Signalling in Plant Root Structures
Por: Leslie Ventimiglia, et al.
Publicado em: (2020-11-01)

Suppression of VEGFD expression by S-nitrosylation promotes the development of lung adenocarcinoma
Por: Qiangqiang He, et al.
Publicado em: (2022-08-01)

De‐nitrosylation Coordinates Appressorium Function for Infection of the Rice Blast Fungus
Por: Hong Hu, et al.
Publicado em: (2024-07-01)

Role, Targets and Regulation of (de)nitrosylation in Malignancy
Por: Salvatore Rizza, et al.
Publicado em: (2018-09-01)

S‐Nitrosoglutathione Reductase Deficiency Causes Aberrant Placental S‐Nitrosylation and Preeclampsia
Por: Shathiyah Kulandavelu, et al.
Publicado em: (2022-03-01)

Protein S-nitrosylation regulates proteostasis and viability of hematopoietic stem cell during regeneration
Por: Weiwei Yi, et al.
Publicado em: (2021-03-01)

Exogenous Nitric Oxide Enhances Disease Resistance by Nitrosylation and Inhibition of S-Nitrosoglutathione Reductase in Peach Fruit
Por: Zifei Yu, et al.
Publicado em: (2020-05-01)

Structural snapshots of nitrosoglutathione binding and reactivity underlying S-nitrosylation of photosynthetic GAPDH
Por: Edoardo Jun Mattioli, et al.
Publicado em: (2022-08-01)

S-Nitrosoglutathione formation at gastric pH is augmented by ascorbic acid and by the antioxidant vitamin complex, Resiston
Por: Vitali I. Stsiapura, et al.
Publicado em: (2018-01-01)

Canavanine-Induced Decrease in Nitric Oxide Synthesis Alters Activity of Antioxidant System but Does Not Impact S-Nitrosoglutathione Catabolism in Tomato Roots
Por: Pawel Staszek, et al.
Publicado em: (2019-09-01)

The Peroxidatic Thiol of Peroxiredoxin 1 is Nitrosated by Nitrosoglutathione but Coordinates to the Dinitrosyl Iron Complex of Glutathione
Por: Daniela R. Truzzi, et al.
Publicado em: (2020-03-01)

Role of Nitric Oxide and Protein S-Nitrosylation in Ischemia-Reperfusion Injury
Por: Hyang-Mi Lee, et al.
Publicado em: (2021-12-01)

Redox regulation of mitochondrial function with emphasis on cysteine oxidation reactions
Por: Ryan J. Mailloux, et al.
Publicado em: (2014-01-01)

Nitric oxide-based regulation of metabolism: Hints from TRAP1 and SIRT3 crosstalk
Por: Fiorella Faienza, et al.
Publicado em: (2022-07-01)

GSNOR facilitates antiviral innate immunity by restricting TBK1 cysteine S-nitrosation
Por: Qianjin Liu, et al.
Publicado em: (2021-11-01)

Dissecting the integrative antioxidant and redox systems in plant mitochondria. Effect of stress and S-nitrosylation.
Por: Juan José Lázaro, et al.
Publicado em: (2013-11-01)

S-Nitroso Human Serum Albumin Enhances Left Ventricle Hemodynamic Performance and Reduces Myocardial Damage after Local Ischemia–Reperfusion Injury
Por: Daniele Linardi, et al.
Publicado em: (2024-06-01)

Downregulation of thioredoxin-1-dependent CD95 S-nitrosation by Sorafenib reduces liver cancer
Por: Raúl González, et al.
Publicado em: (2020-07-01)

NO better way to protect the heart during ischemia-reperfusion: to be in the right place at the right time.
Por: Charlotte eFarah, et al.
Publicado em: (2015-02-01)

Nitric Oxide-induced Protein S-nitrosylation Causes Mitochondrial Dysfunction and Accelerates Post-ovulatory Aging of Oocytes in Cattle
Por: Ying-Jie Niu, et al.
Publicado em: (2020-03-01)

SOD1 aggregation in astrocytes following ischemia/reperfusion injury: a role of NO-mediated S-nitrosylation of protein disulfide isomerase (PDI)
Por: Chen Xueping, et al.
Publicado em: (2012-10-01)

Nitrosative stress and redox-cycling agents synergize to cause mitochondrial dysfunction and cell death in endothelial cells
Por: Anne R. Diers, et al.
Publicado em: (2013-01-01)

Gender differences in S-nitrosoglutathione reductase activity in the lung.
Por: Kathleen Brown-Steinke, et al.
Publicado em: (2010-11-01)

Systems Biology Reveals S-Nitrosylation-Dependent Regulation of Mitochondrial Functions in Mice with <i>Shank3</i> Mutation Associated with Autism Spectrum Disorder
Por: Maryam Kartawy, et al.
Publicado em: (2021-05-01)

The 2-Oxoglutarate Carrier Is S-Nitrosylated in the Spinal Cord of G93A Mutant hSOD1 Mice Resulting in Disruption of Mitochondrial Glutathione Transport
Por: Daniel A. Linseman, et al.
Publicado em: (2022-12-01)

Reductive nitrosylation of Iron(III) complexes of tetradentate ligands
Por: Aswini Kalita
Publicado em: (2023-12-01)

The evolution of S-nitrosylation detection methodology and the role of protein S-nitrosylation in various cancers
Por: Feng Liang, et al.
Publicado em: (2024-12-01)

Putative Connections Between Nitrate Reductase S-Nitrosylation and NO Synthesis Under Pathogen Attacks and Abiotic Stresses
Por: Yu-Fan Fu, et al.
Publicado em: (2018-04-01)

Mitochondrial K+ transport and cardiac protection during ischemia/reperfusion
Por: R.S. Carreira, et al.
Publicado em: (2005-03-01)

S-nitrosoglutathione reductase disfavors cadmium tolerance in shoots of Arabidopsis
Por: Meiyan Guan, et al.
Publicado em: (2024-11-01)

Perspectives on mitochondrial relevance in cardiac ischemia/reperfusion injury
Por: Gaia Pedriali, et al.
Publicado em: (2022-12-01)

Cardiac damage following renal ischemia reperfusion injury increased with excessive consumption of high fat diet but enhanced the cardiac resistance to reperfusion stress in rat
Por: Priyanka N. Prem, et al.
Publicado em: (2023-11-01)

Cardioprotective effects of Prolame and SNAP are related with nitric oxide production and with diminution of caspases and calpain-1 activities in reperfused rat hearts
Por: Nadia Giovanna Román-Anguiano, et al.
Publicado em: (2019-07-01)

Global Proteome-Wide Analysis of Cysteine S-Nitrosylation in <i>Toxoplasma gondii</i>
Por: Zexiang Wang, et al.
Publicado em: (2023-10-01)

Mitochondrial Quality Control: Role in Cardiac Models of Lethal Ischemia-Reperfusion Injury
Por: Andrew R. Kulek, et al.
Publicado em: (2020-01-01)

Oral nitrite treatment increases S-nitrosylation of vascular protein kinase C and attenuates the responses to angiotensin II
Por: Lucas C. Pinheiro, et al.
Publicado em: (2021-01-01)

Increased Nitrosoglutathione Reductase Activity in Hypoxic Pulmonary Hypertension in Mice
Por: Xiling Wu, et al.
Publicado em: (2010-01-01)

The Role of Mitochondria in the Mechanisms of Cardiac Ischemia-Reperfusion Injury
Por: Andrey V. Kuznetsov, et al.
Publicado em: (2019-10-01)

Rapid and selective generation of H2S within mitochondria protects against cardiac ischemia-reperfusion injury
Por: Jan Lj. Miljkovic, et al.
Publicado em: (2022-09-01)